paper writing
paper
6
Individual:Analyzing Published Research Articles (IAPRA) Paper
Purpose
· The purpose of this paper is to interpret the article as most relevant to the group topic.
· Analyze one primary data research article most relevant to your group topic and research question.
Course Outcomes
This assignment enables the student to meet the following course outcomes:
CO 2: Apply research principles to the interpretation of the content of published research studies (PO#4 & 8).
CO 4: Evaluate published nursing research for credibility and clinical significance related to evidence-based
practice (PO#4 & 8).
Due Date (please see course calendar for specific dates/times)
· Week 4, Part I
· Week 4, Part II
· Week 5, Part III
· Week 5, Part IV
· Week 6, Part V
· Week 6, Part VI
· The Late Assignment Policy applies to this assignment.
Points Possible
: 220 Points
Paper Preparation:
· It is NOT acceptable to use bullet-points in the body of text review paper.
· All review contents must be PARAPHRASED with your OWN words with in-text citations.
· It is NOT acceptable to QUOTE article contents
EXCEPT
the
Purpose of Study
as required.
· Paper must include all required APA-Style/Format
· Do
NOT
leave blank for any of these review elements.
· Any review element left blank will get 0 point: If authors did not provide information or it was not applicable for certain elements, make note such as “No information was given” or “Not applicable”
PLAGIARISM: “Turnitin” Percentage
· Less than 25 percentage: Acceptable percentage.
· Turnitin Draft Submission Box
· Submit your draft of paper into Turnitin Draft Submission Box to check your percentage as many times as needed before you submit your final paper to designated Unit.
· If your Final paper has 25% or higher percentage, you must revise/modify your paper contents
BEFORE
you submit your paper due date and time.
· If your Final paper has 25% or higher percentage
AT/AFTER
you submit your final paper due date and time, Academic Integrity Violation Procedures will be initiated
Academic Integrity Violation Procedure
· Academic Integrity Violation letter will be sent to student
· Assignment Grade will be 0 point
· The violation case will be reviewed, and a further sanction will be determined by the Administrators
Individual Analyzing Published Research Article (IAPRA)
Part I: Research Question, Purpose, Variables and Participants
Research Question
· Clearly and concisely states your group research question as formulated in PICO format.
Purpose of the Study
· Describe the purpose/aim of the study as the author stated in the article: may cut & paste
· Do
NOT
change or modify the purpose statement on the article
Variables
· Identify study variables from the above stated Purpose of Study
· Quantitative Study: Dependent & Independent Variables
OR
Descriptive, Qualitative Study: Variables of Interest
Participants
· Enrollment: How did they recruit/enroll eligible participants in the study?
· Inclusion & Exclusion Criteria: Describe Inclusion & Exclusion Criteria
· Total Participant Numbers: Total numbers of participants in the study
Part II: Intervention Procedures/Obtaining Information Procedures
Quantitative Study
Intervention/Treatment Group
· Describe the intervention contents given to Intervention group
· Describe how the contents were given to Intervention group
· Identify the person who provided Intervention contents to Intervention group
Control Group: If the study has Control Group
· Describe the contents given to Control group
· Describe how the contents were given to Control group
· Identify the person who provided contents to Control group
OR
Descriptive/Qualitative Study: Obtaining Information Procedure
· Describe the detailed procedure for obtaining information/data (i.e. made appointment to meet each participant, visited home/met in clinical setting……etc)
Part III: Data Collection Procedures & Measurement Tools/Instruments
· Describe ALL methods to collect data in detail (i.e. interview, survey, observation……etc.)
· Describe
each
measurement tool/instrument used to measure/assess outcomes in the study in detail.
Part IV: Results/Findings
Participant Characteristics/Sociodemographic Findings
· Describe participant characteristics or sociodemographic status
· Must be objective, descriptive, and comprehensive
· Must describe the findings of Tables/Figures to provide comprehensive information about participant characteristics as article provided.
Study Results/Findings
· Describe
ALL
Other Results/Findings besides above participant characteristics in detail.
· Each result item must include Headings/Subheadings as the article provided.
· Do
NOT
simply saying “pain level was decreased,” “adherence was increased”…etc
· Do
NOT
include contents from Discussion and/or Conclusion in the article.
Part V: Synthesis of Findings
Synthesis of Findings
· Describe the
Rationale/Mechanism
for how/why
Finding
of each intervention/factor helps your Research Question (i.e. how/what mechanism does music therapy help pain, how does sucking stimulation increase oral intake for pre-term infants)
· Should
NOT
repeat same contents you had on Findings section and/or article
· May include citations from other sources for above described rationale/mechanism (i.e. textbooks, CDC…etc)
Nursing Implications
· How the nurses can implement the research findings into nursing practice.
Part VI: Group Article Summary Table (All group members)
· Describe each group member’s article on Research Article Summary Table.
· Use bullet points for each review content
Grading Rubric & Description for IAPRA
Part I (40)
Research Question
5
· Accurately/Clearly states group’s Research Question as your group formulated
Format
5
Followed APA format for paper, in-text citation, references.
Purpose of Study
5
· Describe the purpose of the study as the author stated in the article.
· Do
NOT
change or modify the statement on the article
Variables
10
· Identify study variables from the above stated Purpose of Study
· Quantitative Study: Dependent & Independent variables
OR
· Descriptive, Qualitative Study: Variables of Interest
Participants
5
5
5
· Enrollment: How did they recruit eligible participants in the study?
· Eligibility: Describe Inclusion & Exclusion Criteria
· Numbers: Total numbers of participants in the study
Part II (45)
Intervention Procedures
Obtaining Information Procedures
40
Quantitative Study:
· Intervention Group: Describe the detailed Intervention contents, procedures, and person who provided Intervention for Intervention group.
· Control Group: Describe the detailed contents, procedures, and person who provided contents for Control group
OR
Descriptive Study:
· Describe the detailed procedure for obtaining information/data (i.e. made appointment to meet each participant, visited home/met clinical……etc)
Format
5
Followed APA format for paper and in-text citations
Part III (40)
Data Collection
Measurement Tools
5
35
· Describe ALL data collection methods in detail (i.e. survey, interview, observation)
· Describe each measurement tool/instrument used to measure study outcomes in detail.
Format
5
· Followed APA format for paper and in-text citations
Part IV (50)
Participant Characteristics/Sociodemographic Findings
All other Results/Findings
15
30
· Must be descriptive and comprehensive
· Describe participant characteristics or sociodemographic findings
· Describe the findings of Tables/Figures to provide comprehensive information about participant characteristics as article provided
· Describe
ALL
Other Results/Findings besides above participant characteristics in the article in detail for each Result item
· Each Result item must include Headings/Subheadings of Results as the article provided.
· Do
NOT
simply saying “pain level was decreased,” “adherence was increased”
· Do
NOT
include contents from Discussion and/or Conclusion in the article.
Format
5
· Followed APA format for paper and in-text citations
Part V (20)
Synthesis of Findings
10
· Describe the
Rationale
for how/why
Finding
of each intervention/factor helps your Research Question (i.e. how/what mechanism does music therapy help pain, how does sucking stimulation increase oral intake for pre-term infants)
· Should
NOT
repeat same contents you had on Findings section and/or article
· Should have citation of analyzed article(s)
· May include citations from other sources for above described rationale and mechanism (i.e. textbooks, CDC…etc)
Nursing Implication
5
· How the nurses can implement the research findings into nursing practice?
Format
5
· Followed APA format for paper, in-text citation, references.
Part VI (25)
Article Summary Table (Group)
25
· Describe article on Research Article Summary Table
· Use
bullet points
for each review content
· Submit Table as separate document
Total Points: 220 Points
Cover
©2
0
16 American Association of Critical-Care Nurses doi: http://dx.doi.org/10.4037/ccn201649
8
CE 1.0 hour
Fran Flynn, APRN, MS, BC-CNS
Julie Q. Evanish, RN, BS, PCCN
Josephine M. Fernald, RN, BSN, PCCN
Dawn E. Hutchinson, RN, BSN, PCCN
Cheryl Lefaiver, RN, PhD, CCRP
Progressive Care Nurses
Improving Patient Safety by
Limiting Interruptions During
Medication Administration
BACKGROUND Because of the high frequency of interruptions during medication administration, the
effectiveness of strategies to limit interruptions during medication administration has been evaluated in
numerous quality improvement initiatives in an effort to reduce medication administration errors.
OBJECTIVES To evaluate the effectiveness of
evidence-based strategies to limit interruptions during
scheduled, peak medication administration times in 3 progressive cardiac care units (PCCUs). A sec-
ondary aim of the project was to evaluate the impact of limiting interruptions on medication errors.
METHODS The percentages of interruptions and medication errors before and after implementation of
evidence-based strategies to limit interruptions were measured by using direct observations of nurses
on 2 PCCUs. Nurses in a third PCCU served as a comparison group.
RESULTS Interruptions (P < .001) and medication errors (P = .02) decreased significantly in 1 PCCU after
implementation of evidence-based strategies to limit interruptions. Avoidable interruptions decreased
83% in PCCU1 and 53% in PCCU2 after implementation of the evidence-based strategies.
CONCLUSIONS Implementation of evidence-based strategies to limit interruptions in PCCUs decreases
avoidable interruptions and promotes patient safety. (Critical Care Nurse. 2016;36[4]:19-35)
This article has been designated for CE contact hour(s). The evaluation tests your knowledge of the following objectives:
1. Describe similarities between the principles of the sterile cockpit concept used in the aviation industry and the Nurses Uninterrupted Passing Medications Safely
(NUPASS) guidelines to promote safety
2. Discuss the current evidence supporting use of interruption limiting strategies to reduce medication administration errors in the acute care setting
3. Implement evidence-based strategies to limit interruptions during medication administration
To complete evaluation for CE contact hour(s) for test #C1642, visit www.ccnonline.org and click the “CE Articles” button. No CE test fee for AACN members.
This test expires on August 1, 2019.
The American Association of Critical-Care Nurses is an accredited provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on
Accreditation. AACN has been approved as a provider of continuing education in nursing by the State Boards of Registered Nursing of California (#01036) and Louisiana (#LSBN12).
N
urses play a critical role in promoting patient safety through surveillance and inter-
ception of errors that cause patient harm as hospitals and health care systems strive
to become high-reliability organizations.1 The Institute of Medicine estimates that
medication errors result in several thousand deaths annually.2 Interruptions during
complex or high-risk activities such as medication administration increase risk of
www.ccnonline.org CriticalCareNurse Vol 36, No. 4, AUGUST 2016 19
20 CriticalCareNurse Vol 36, No. 4, AUGUST 2016 www.ccnonline.org
Authors
Fran Flynn was the advanced practice nurse on one of the progressive cardiac units at the time of the project and is now the advanced practice
nurse for the inpatient palliative care service, Advocate Christ Medical Center, Oak Lawn, Illinois.
Julie Q. Evanish was a bedside nurse in one of the progressive cardiac units at the time of the project and is now working in the outpatient
pain clinic, Advocate Christ Medical Center.
Josephine M. Fernald was a bedside nurse in one of the progressive cardiac care units at the time of the project and is now working in the
outpatient heart failure clinic, Advocate Christ Medical Center.
Dawn E. Hutchinson was a bedside nurse in a progressive cardiac care unit when the study was done and is now a clinical informatics
specialist, Advocate Christ Medical Center.
Cheryl Lefaiver was the professional nurse researcher for the medical center when the study was done and is now manager of patient-centered
outcomes research for Advocate Center for Pediatric Research, Advocate Christ Medical Center.
Corresponding author: Fran Flynn, APRN, MS, BC-CNS, Advocate Christ Medical Center, 4400 W 95th St, Oak Lawn, IL 60453 (e-mail: fran.flynn@advocatehealth.com).
To purchase electronic or print reprints, contact the American Association of Critical-Care Nurses, 101 Columbia, Aliso Viejo, CA 92656. Phone, (800) 899-1712 or (949)
362-2050 (ext 532); fax, (949) 362-2049; e-mail, reprints@aacn.org.
patient harm, and strategies to reduce interruptions
and manage them appropriately are needed.3 On the
basis of the current evidence, the Institute of Medicine
recommends that organizations adopt strategies to
reduce interruptions during medication administration
as part of a comprehensive medication safety program.
2
The quality improvement project described here
evaluates the impact of adopting evidence-based strate-
gies to limit interruptions during medication adminis-
tration in 2 progressive cardiac care units (PCCUs) at
Advocate Christ Medical Center, a Magnet-designated
tertiary care center in the Midwest. A third PCCU served
as a comparison unit and, therefore, did not adopt the
interruption-limiting strategies. A secondary aim of the
project was to evaluate how limiting interruptions
affected medication errors in this setting.
Background
In a plenary speech at the 2008 National Teaching
Institute, the former president of the American Associa-
tion of Critical-Care Nurses challenged more than 9000
nurses in attendance to avoid multitasking and interrup-
tions when
administering
medications
in order to
prevent medi-
cation errors.
Attendance at this speech was the inspiration for this
project and became the springboard for addressing
existing nursing concerns about interruptions.
Review of the Literature
Observational studies describe the high cognitive
work of nurses coupled with frequent interruptions and
multitasking behaviors during direct patient care activ-
ities in acute care settings.4-8 The work environment is
error-prone, especially during complex or high-risk
activities, because interruptions and multitasking
behaviors create conditions affecting working memory
and attention resources.9,10 Nurses’ cognitive processes
during medication administration are complex and
require a high degree of critical thinking and vigilance
to prevent patient harm.11 Medication administration
is one of the most frequently interrupted nursing
activities,4,6,12 and strategies to limit interruptions are
recommended to improve patient safety.
Studies describing the frequency and characteristics
of interruptions during medication administration show
that nurses have little protected time to focus on medica-
tion administration because of short, frequent interrup-
tions.6-9,12,13 The most common source of interruptions is
interactions with other nursing staff seeking information
or assistance with patient care.13 The frequency of inter-
ruptions by other care providers varied significantly
across studies.13,14 Although they were not the most fre-
quent source of interruptions, phone calls were identi-
fied by nurses as one of the most disruptive sources of
interruptions and one of the most likely sources of inter-
ruptions to be associated with medication errors.8,12
System failures such as missing medications and access
to equipment and supplies were also identified as sources
of interruptions that are potentially avoidable.7,8,12-16
Other avoidable interruptions cited in the literature are
the tendency of nurses to interrupt each other with
conversations unrelated to medication administration7,17-19
while preparing medications and to respond immedi-
ately to requests from others when interrupted.7,15,20
These findings support the idea that interruptions are
an accepted part of nursing practice and suggest the
Attendance at the National Teaching
Institute was the inspiration for this
project and the springboard for
addressing existing nursing concerns
about interruptions.
www.ccnonline.org CriticalCareNurse Vol 36, No. 4, AUGUST 2016 21
need for culture change to limit avoidable interruptions,
especially during complex or high-risk activities such as
medica
tion administration.
Development and testing of strategies to limit inter-
ruptions during the medication administration process
are primarily based on research from the aviation indus-
try. In 1981, the Federal Aviation Authority mandated
use of standard operating procedures to create a sterile
cockpit situation aimed at reducing unsafe working con-
ditions and preventing errors during high-risk activities
such as aircraft takeoff and landing. Essential aspects of
the sterile cockpit concept include eliminating interrup-
tions, prohibiting communication unrelated to critical
tasks, and maximizing teamwork and coordination
during high-risk activities.21,22 The majority of published
clinical initiatives to limit interruptions during medica-
tion administration are nurse-led quality improvement
projects involving implementation of a set of strategies
to limit interruptions (Table 1). The goal of these initia-
tives is to provide nurses with time to remain focused
and undisturbed while preparing and administering
medications. Direct observations of nurses preparing
and administering medications during peak, scheduled
administration times were used to study interruptions
in these quality improvement projects. Results of these
projects demonstrate that implementation of a set of
strategies is effective in limiting interruptions and may
improve patient safety by decreasing medication errors.
To date, 1 study3 examining the direct relationship
between work interruptions and hospital medication
administration errors has been published. Results of this
landmark study demonstrated that the frequency of
interruptions during medication administration increased
the risk of both the number and severity of medication
errors. Table 2 provides a detailed analysis of the litera-
ture regarding cognitive work of nurses and the com-
plexity of the work environment, interruptions during
medication administration, strategies used to limit inter-
ruptions during medication administration, and the
contribution of interruptions to medication errors.
Introduction to the Progressive Cardiac
Care Quality Improvement Project
The PCCU quality improvement project was developed
and implemented on the basis of the work of Nguyen
and colleagues.25 In the quality improvement project
presented here, the project team implemented a set of
evidence-based strategies to limit interruptions during
scheduled, peak medication administration times in
the progressive cardiac care setting. The project team
embedded the interruption strategies into practice guide-
lines to promote communication, coordination of care,
and teamwork during medication administration. The
guidelines are referred to as the “NUPASS guidelines,” on
the basis of the project’s name: Nurses Uninterrupted
Passing Medications Safely (Table 3).
The project’s conceptual framework is
based on the
medical center’s Evidence-Based Practice (EBP) Model
(Figure 1). The EBP model was adopted and modified
on the basis of the Iowa model.30 Using the EBP model
as a guide, the project team initiated a pilot practice
change based on the current evidence supporting use
of strategies to limit interruptions during medication
administration. The pilot practice change was designed
to answer 2 questions: (1) Does implementation of the
NUPASS guidelines decrease interruptions during medi-
cation administration? and (2) Do medication errors
decrease following implementation of NUPASS guide-
lines? The pilot practice change was conducted on 2 of
the 3 PCCUs; PCCU1 and PCCU2 were the intervention
units that implemented the NUPASS guidelines, and
PCCU3 served as
a comparison unit.
Patients cared for in the high-acuity PCCUs typically
included patients who required invasive diagnostic and
interventional cardiovascular procedures, cardiovascular
surgery, and arrhythmia management. Common medi-
cal diagnoses included acute coronary syndrome, heart
Table 1 Evidence-based strategies to limit
interruptions during medication administration
1. Hourly patient rounds23
2. Scripts for triage of phone calls17,22,24-26
3. Protected time for passing medications without
interruptions17,22,
2
5
4. Signage to remind staff to limit interruptions12,17,22,24-26
5. “No interruption zone”/“quiet zone” established in
medication rooms17,24-27
6. Phone calls to nurses limited during medication
administration17,25
7. Nurses don visible wear as a nonverbal cue that they
are administering medications and are not to be
disturbed12,17,22,26
8. Distribution of patient/family education materials about
limiting interruptions during medication administration12,17
22 CriticalCareNurse Vol 36, No. 4, AUGUST 2016 www.ccnonline.org22 C i i lC N
Table 2 Detailed review of the literature
Reference
Potter et al,4 2005
Eisenhower et al,11 2007
Kalisch and Aebersold,5
20
1
0
Cornell and Riordan,9
2011
Kreckler et al,6 2008
Biron et al,7 2009
Palese et al,8 2009
Biron et al,13 2009
Sample/setting
Convenience sample of 7 nurses with
acute care experience and clinical
background
Large, tertiary medical center in the
Midwest
Convenience sample of 40 nurses
working in intermediate medical-
surgical intensive care unit
(M/S ICU) and ante/postpartum unit
Large, tertiary teaching hospital in
the Northeast
Convenience sample of 36 nurses
from 5 M/S units, 1 ICU, and 1
progressive care unit
Seven patient care units in 2
Midwestern hospitals including
an academic medical center and a
community-based teaching hospital
Convenience sample of 19 nurses
from 2 hospitals including 8 nurses
on an M/S unit at a suburban,
acute care hospital and 11 nurses
on a pediatric oncology unit at a
pediatric research hospital in the
United States
Convenience sample of nurses
working on a 37-bed surgical unit
at a teaching hospital in the United
Kingdom
Convenience sample of 18 nurses
working on a medical unit at a
tertiary care teaching hospital in
Quebec
A convenience sample of nurses
working on 7 surgical units across
multiple, similar type hospitals in
Northern Italy
Articles from 1980 to 2008 were
analyzed
Design/procedures
Mixed method ethnographic observa-
tional study combining quantitative
human factor engineering techniques
with summative nurse interviews
Nurses were observed for a total of 48 h
Descriptive study with semistructured
interviews
Observational study
A previously validated instrument
referred to as the “Communication
Observation Tool” was used by 4
trained staff nurses to collect data
For the purpose of this study, both
procedural failures and medication
administration errors were counted
as errors
Observational study limited to nurs-
ing activities outside of the patient’s
room during 85.2 h of observation
Observational study
Thirty-eight medication passes were
observed in 5 weeks
Observational study
Descriptive data included source and
duration of interruptions, nursing
tasks and location during interrup-
tions and strategies used by nurses
to manage interruptions
Mixed-method study combining
observation of nurses during medica-
tion administration followed by nurse
interviews during a 3-month period
Systematic review
Fourteen of 23 studies selected for
analysis reported observation times
and interruption frequencies and
therefore, underwent further analysis
Purpose
Analyze nurses’ cognitive work
and how environmental fac-
tors create disruptions that
pose risk for medical errors
Describe nurses’ thinking
during medication admin-
istration before and after
implementation of bar-code
medication scanning (point-
of-care technology)
Evaluate the type and extent
of work interruptions, multi-
tasking, and errors
Assess the complexity of
nurse workflow and review
its cognitive implications
Determine the time required
by nurses to deal with inter-
ruptions and the nature of
nurses’ work interruptions
(WIs) during medication
administration
Document characteristics of
nurses’ WIs during medi-
cation administration
Examine the frequency and
perceived risk of WIs during
medication administration
Review the evidence on
nurses’ interruption rates,
characteristics of WIs, and
contribution of WIs to medi-
cation administration errors
A. Cognitive work of nurses and complex work environment
B. Interruptions during medication administration
www.ccnonline.org CriticalCareNurse Vol 36, No. 4, AUGUST 2016 23C i i lC N 23
Findings/conclusions
Nurses averaged 9 cognitive shifts per hour or a shift in attention focus once every 6-7 min
The human factor engineer found 5.9 interruptions per hour and the nurse researcher found an average of 3.4 interruptions per hour
Twenty-two percent of interruptions occurred in the medication room during medication preparation, and no attempt was made by
nurses to control sources of the interruptions
Nurses’ constant vigilance to provide the appropriate medication was a common theme found in the content analysis
Nurses’ thinking was categorized into 10 descriptive categories; the only change in thinking after implementing bar-code scanning was
the descriptive category related to checking medications
Key aspects of critical thinking identified included assessment of the patient before and after administration of medications, interpretation
and verification of relevant laboratory data, application of knowledge to specific patient situations, anticipatory problem solving related
to the patient’s expected clinical trajectory and consultation with health care team members to prevent medication errors and adverse
drug events
The mean interruption rate observed at the 2 hospitals was 10 interruptions per hour resulting in a break in task more than 1/3 of the time
Interruptions occurred every 6 minutes for hospital 1 and every 4.5 min for hospital 2; nurses were interrupted during medication
administration 57% and 36% of the time in hospital 1 and hospital 2, respectively
Nurses engaged in multitasking an average of 30% and 40% of the time in hospital 1 and hospital 2, respectively
Significantly more interruptions (P < .001), multitasking (P < .001), and breaks in task (P < .001) occurred in ICUs than in the M/S units
No more errors were found when nurses were interrupted or multitasking vs when nurses were not interrupted or multitasking
More than 2000 tasks were recorded on each unit during 35.7 h of observation on the M/S unit and 49.5 h of observation on the pediatric
oncology unit
The duration of tasks was short with a mean of 62.4 (SD, 127.7) s and 49.5 (SD, 81.6) s on the M/S unit and pediatric oncology unit,
respectively
The reason for switching tasks (self-directed or external) was not discernible
Nurses frequently changed locations when switching tasks
Medication passes were interrupted a mean of 11% of the time
Two-thirds of the medication passes were interrupted with a mean of 2.61 interruptions per medication pass
The 3 most frequent sources of interruptions in descending order were (1) interruptions by the nurse administering medication (self-initiated),
(2) interruptions by physicians, and (3) interruptions by other staff and patients
Phone calls were not the most frequent source of interruption; however, they were found to be significant because of their longer duration
WIs averaged 6.3 per hour (5.2 per hour during medication preparation and 6.8 per hour during medication administration)
WIs were of short duration with a mean of 1 min 32 sec (SD, 2 min)
The most frequent WIs during medication preparation were by nurse colleagues followed by system failures due to missing medication
and equipment
Nurses preparing medications were interrupted by other nurses for personal matters 36% of the time and to exchange verbal reports
22% of the time
The most frequent WIs during medication administration were self-initiated and by patients during direct patient care activities
Nurses handled WIs immediately more than 98% of the time; the proportion of WIs handled immediately was similar during both
medication preparation and administration (98.8% and 97.6%, respectively)
A mean of 1 interruption per 3.2 drugs administered occurred during medication administration
When there was an increased number of drugs per medication pass for a single patient, the number of interruptions increased significantly
(P = .05).
Nurses intervened immediately when interrupted 96% of the time
Nurses perceived interruptions related to management of phone calls to be the highest risk for error during medication administration
Pooled data from 14 studies found WIs occurred at a rate of 6.7 interruptions per hour
The majority of interruptions were self-initiated by nurses administering medications during face-to-face interactions, occurred most
frequently during direct patient care, and were of short duration ranging from 45 sec to 1.2 min
Only 1 nonexperimental study documented the contribution of interruptions to medication errors with evidence of a significant association
(P = .01).
Continued
Table 2 Continued
Reference
Pape,22 2003
Nguyen et al,²5 2009
Anthony et al,27 20
10
Freeman et al,17 2013
Williams et al,26 2014
Sample/setting
Convenience sample of M/S unit
nurses were observed during a
single medication pass for assigned
patients in a 520-bed acute care
hospital in Texas
Forty-five nurses working on a 25-bed
M/S unit at an academic teaching
hospital in Northern California
The project was conducted in
partnership with a larger quality
improvement (QI) initiative spon-
sored by the Integrated Nurse
Leadership Program aimed at
improving patient safety and involved
7 hospitals in the San Francisco Bay28
Convenience sample of medical ICU
and surgical ICU nurses working in
a tertiary academic medical center
in Cleveland, Ohio
Convenience sample of 99 nurses in
a cardiac and thoracic surgical
step-down unit at a large, academic
medical center in the Midwest
Convenience sample of nurses
working in a surgical progressive
care unit (52 before intervention
and 48 after intervention)
Academic medical center in the
southeastern United States
Design/procedures
Quasi-experimental 3-group study
design including a comparison
group and 2 intervention groups
A validated instrument referred to
as the Medication Administration
Distraction Observation Sheet
(MADOS) was used to count
distractions
A longitudinal observational QI
project
One hundred medication passes
were observed before the interven-
tion and at 6 months and 1 year
after the intervention
Observational pilot project
A “no interruption zone” (NIZ) was
created by placing red tape around
all medication preparation areas to
signify that nurses were not to be
disturbed while preparing
medications
The number of interruptions before
and 4 weeks after the NIZ was
implemented were measured
Nurses observed were blinded to the
purpose of the study
Observational QI project.
A modified version of the MADOS
instrument was used to count the
number and type of interruptions
Observational study
Distractions and interruptions were
measured using the MADOS instru-
ment before and 2 months after
implementation of 5 evidence-
based safety strategies including
nursing staff education, use of a
medication safety vest, NIZ in
medication preparation areas,
signage on the unit and patient
rooms, and a resource tool for
scripting responses to interruptions
Purpose
Test the effectiveness of 2
interventions (“focused”
protocol and “medsafe”
protocol) to reduce distrac-
tions during medication
administration in comparison
to usual practice
Determine which distractors
are more predictive of nurses
being distracted during
medication administration
Evaluate whether a safety
initiative referred to as the
“Med Pass Time Out” was
effective and sustainable in
reducing medication
administration errors
Evaluate the effect of a NIZ on
the number of interruptions
during medication preparation
Determine whether implemen-
tation of a set of interventions
would reduce interruptions
during medication adminis-
tration
A secondary project goal was
to reduce medication errors
Interventions implemented
were previously described
in the literature, including
wearing a lighted lanyard
during medication adminis-
tration, triage of phone
calls, creating an NIZ in the
medication preparation
area, signage, and staff and
patient/family education
To evaluate the effectiveness
of implementing 5 evidence-
based safety strategies to
reduce distractions and
interruptions during
medication preparation
C. Strategies to limit interruptions
Findings/conclusions
Significant differences in the mean number of distractions were found between the comparison group and both intervention groups
(P < .001) as well as between the 2 intervention groups (“focused” protocol [P = .01] and “medsafe” protocol [P < .001])
The significant difference between the 2 intervention groups was attributed to use of a visible symbol that the nurse wore during medication
administration (a red vest with the lettering “Medsafe Nurse, Do Not Disturb”)
Conversation accounted for the majority (93%) of the variance in distractions, followed by interruptions by personnel (90%) and loud noises
Uninterrupted time increased from 81% to 99% of the time at 6 months and 1 year after implementation of the “Med Pass Time Out”
Medication errors decreased from 2% to 1% at 6 months and improvement was sustained at 1 year
No statistical analysis
The number of interruptions decreased by 40.9% (from 31.8% to 18.8%) after implementation of the NIZ (P = .03).
The proportion of interruptions initiated by nurses preparing medications (self-initiated interruptions) decreased from 25% to 0%
following implementation of the NIZ
Mean number of interruptions decreased from 3.29 to 1.18 during medication administration
Medication errors decreased by 28 events when compared with the same time period the year before
Patients, nurses, and patients’ family members represented the top 3 sources of interruptions before implementing interventions to
reduce interruptions; 1 month after implementation of the interventions, no interruptions were made by family members
No statistical analysis
Four types of distractions and interruptions decreased significantly after implementation of the safety strategies including those
initiated by (1) physicians, nurse practitioners, and physician assistants (P = .001), (2) phone calls and pages (P = .001), (3) other
personnel (P < .001), and (4) conversations unrelated to medication administration (P = .002)
Total reported adverse drug events decreased from 10 to 4 (60%)
Nurse were not found to be compliant with wearing the safety vest or using the resource tool when responding verbally to interruptions
but were compliant with use of signage and the NIZ when preparing medications
Continued
Table 2 Continued
Reference
Westbrook et al,3 2010
Hopkinson and
Jennings,29 2013
Raban and Westbrook,21
2014
Sample/setting
Convenience sample of 98 nurses
from 6 units at 2 major teaching
hospitals in Sydney, Australia
A total of 31 articles published
between 2001 and 2011 were
selected for analysis, including 12
that specifically examined nurse WIs
during medication administration
Studies were conducted in 7 countries,
including 14 studies conducted in
US acute care facilities
Ten studies meeting inclusion criteria
and published up to September 2012
were analyzed
Eight of the 10 studies were
published in North America
All studies used direct observation
for data collection, but studies were
not limited to the acute care setting
Design/procedures
Observational study
A total of 505 hours of observation
was conducted during an
18-month period
Systematic review
Most studies used a nonexperimental
design and involved direct observa-
tion methods for data collection
Systematic review
Studies included for analysis were
observational studies that reported
quantitative data on interruptions
or medication administration errors
with a pre- and postintervention
design or use of a comparison group
Studies included were not limited to
the acute care setting
Purpose
Examine the direct relation-
ship between WIs and
hospital medication
administration errors
Examine empirical evidence
from studies of nurse WIs
in the acute care setting
Assess evidence of the
effectiveness of interven-
tions aimed at reducing
interruptions during
medication administration
on
interruption and
medication administration
error rates
D. Contributions of interruptions to medication errors
Table 3 Nurses Uninterrupted Passing Medications Safely (NUPASS) guidelines
Before administering medications
1. Nurses update the charge nurse (CN) before administering medications if there are changes in patients’ status that affect
scheduled procedures or transport needs; otherwise, nurses simply place a colored magnet next to their name on the
assignment board (board in clear view at the front desk) to indicate that they are administering medications.
2. Nurses dock their phones just outside the medication room before entering to prepare medications. Docked phones are
programmed to forward all calls to the front desk.
3. Nurses don a yellow safety sash before leaving the medication room to administer medications.
After administering medications
1. Once medication administration is compete, nurses return their yellow safety sash to the medication room, pick up their
docked phone, remove the colored magnet from the assignment board, and check at the front desk for any new messages
recorded on a communication log.
General practice progressive cardiac care unit (PCCU) guidelines
1. Nurses perform hourly rounds on odd hours (corresponds with peak, scheduled medication times). Patient care assistants
(PCAs) perform hourly rounds on even hours.
2. Phone and face-to-face requests by family for patient information are screened for a password in accordance with the medical
centers’ policy for compliance with the Health Insurance Portability and Accountability Act (HIPAA) before contacting the
assigned nurse.
3. Nursing staff use key phrases to respond to nonemergent requests or inquiries: “For the safety of our patients,” we do not
interrupt the nurse while administering medications. Is there something I can help you with?
4. Unit secretaries refer requests/inquiries to the CN only in situations where they cannot triage or manage the communication
themselves.
5. Prespecified peak, scheduled medication administration times for “no interruption” except emergencies: 5 AM-7 AM,
8 AM-10 AM, and 8 PM-10 PM. Emergencies include imminent patient safety concerns, patients’ request for pain medica-
tion, emergency response to cardiac arrhythmia alert, need to communicate information only assigned nurse has specific
knowledge of in a critical event, rapid response, or cardiopulmonary arrest of assigned patient.
6. Signage on closed medication room door reminds staff that medication room is a “quiet zone.”
7. “No interruption zone” (NIZ) outlined on floor in the medication room next to the medication storage/delivery system.
8. “Daily Patient Care Activity Flowsheet”: Day-shift CN receives a brief report on each patient from the assigned nursing staff,
including scheduled procedures and patient transport needs for the next 24 hours before 8 AM daily during “huddle-up.”
This information is logged by the day-shift CN on a structured daily flow sheet and is updated by the evening and night
CNs on the basis of the corresponding shift reports by nursing staff to assist with coordination of patient care activities.
9. “Communication log”: used to document nonurgent messages while nurses are administering medications.
10. Patient/family education tool: written patient/family education provided on admission to help explain the pilot practice change.
www.ccnonline.org CriticalCareNurse Vol 36, No. 4, AUGUST 2016 27
failure, and uncontrolled atrial fibrillation. Patient care
was delivered by nursing staff including registered nurses
and certified nursing assistants referred to as patient care
associates (PCAs). The nurse to patient ratio was 1 to 4
on the day and evening shifts and 1 to 5 on the night shift.
The number of beds on each unit was from 36 to 46, and
the daily patient census was from 34 to 39. Technol-
ogy used to support the medication administration pro-
cess at the time of the pilot practice change included a
centralized medication storage system, computer phy-
sician order entry, and electronic medication administra-
tion record. Bar-code scanning of medications was not
available at the time of the pilot practice change. Geo-
graphic differences in the layout of the PCCUs included
the number of medication rooms and the number of
semiprivate versus private patient rooms. The project team
for the pilot practice change consisted of 5 bedside nurses
from the PCCUs, an advanced practice nurse, and a
nurse researcher.
Methods
Data Collection
The pilot practice change was conducted for 18
months. The baseline percentages of interruptions
and medication errors were measured in July 2009,
and these measures were repeated after implementa-
tion of the NUPASS guidelines in December 2010
(Figure 2). A convenience sample of nurses from each
PCCU was randomly observed during peak, scheduled
medication administration times. Nurses were aware
of being observed during data collection. Data collec-
tors used the following script to explain why they
were conducting observations during medication
administration:
We are conducting a quality improvement
project to identify opportunities to improve
patient safety during medication administra-
tion. All data [are] being collected anony-
mously and [do] not include the identity of
the nurses being observed during medica-
tion administration.
Observations were conducted during prespecified
times (5 AM – 7 AM, 8 AM – 10 AM, and 8 PM – 10 PM). The
number of observations conducted for each prespecified
time was based on the mean number of medications
scheduled during these peak administration times. The
project team staff nurses collected all data and observed
medication passes on PCCUs other than their own.
Two standardized data collection tools referred to as
the Medication Administration Accuracy Observation
f il d t ll d t i l fib ill ti P ti t d h d f i l
Findings/conclusions
Each interruption was associated with a 12.1% increase in procedural failures and a 12.7% increase in medication errors
The frequency of interruptions during medication administration increased the risk of both the number and severity of medication errors
The estimated risk of a major error, defined as an error most likely to cause harm, permanent damage or death, doubled from 2.3%
with no interruption to 4.7% with 4 or more interruptions during administration of scheduled medications to a single patient
The evidence for reducing medication errors by limiting interruptions remains at the level of descriptive research because the majority
of projects were nurse-led QI projects
Interpretation of results was limited because of the different methods used for unit sampling, measuring, and defining interruptions
Five studies had statistically significant changes in the number of interruptions before and after implementation of a set of interventions;
interruptions decreased in 4 studies and increased in 1 study
The 3 studies that measured changes in medication error rates showed reductions, but all 3 studies implemented multiple interventions
besides those aimed at reducing interruptions
Weak evidence of the effectiveness of interventions intended to reduce interruptions and medication error rates exists primarily owing
to the small number of studies, and the lack of robust study design, appropriate statistical analyses, and small sample size
28 CriticalCareNurse Vol 36, No. 4, AUGUST 2016 www.ccnonline.org
Code Sheet and the Medication Administration Accuracy
Record Review Worksheet developed by the California
Nursing Outcomes Coalition (CALNOC) were modified
and adapted for use with written permission of CALNOC
(March 26, 2009). Before implementation of the pilot
practice change, an interrater reliability study involving
30 observations (10 per unit) was conducted to establish
agreement among trained data collectors and resulted
in 96% agreement. Operational definitions used for the
purposes of data collection during the pilot practice
project are listed in Table 4.
During observations, the data collectors were blinded
to the electronic medication orders to prevent confirma-
tion bias. The Medication Administration Accuracy
d h d h d d
Figure 1 Evidence-based practice (EBP) model.
Abbreviations: AHC, Advocate Health Care; APN, advanced practice nurse; IRB, institutional review board; NRC, Nursing Research Committee; PDSA, plan, do, study, act;
PICO, problem or population, intervention, comparison, and outcome.
Iowa Model adapted from Titler et al,30 with permission. ©University of Iowa.
Use the PICO Framework Worksheet (1)
to develop your PICO question.
Conduct Research
IRB Process
Identify Clinical Question/Problem (PICO)
Request to Investigate Practice
Complete Synthesis of
Evidence Worksheet
**Present to Council
(The council will depend
upon the type of project)
Pilot Practice Change
AHC Project Completion and Education
Planning Form (7)
Communicate Change
Monitor and Analyze Outcome Data
Nursing Research
Resource: AHC NRC
IRB Submission &
Review Process (9)
Complete the Practice Investigation Approval Form (2)
to assess a need for change and identify stakeholders.
Meet with librarian and/or APN and use the Evidence Matrix
(3) and Level of Evidence Reference (4) as tools for your
literature search. Critique and synthesize evidence using
the Evidence Synthesis Worksheet (5).
Refer to your site EBP or Research representative
to determine appropriate council
Yes
Yes
No
EVIDENCE-BASED PRACTICE (EBP) MODEL
NO- Cycle
complete
go back to
literature
Use the PDSA model to plan & conduct the pilot.
Resources: PDSA for Piloting Change Worksheet (6)
To implement project recommendations & conduct
education use the AHC Project Completion and
Education Planning Form (7)
Practice Change Communication
** Inform Shared Governance
Councils when needed
(ie, education and/or practice)
Is There
Sufficient
Evidence?
Adopt practice
change?
www.ccnonline.org CriticalCareNurse Vol 36, No. 4, AUGUST 2016 29
Observation Code Sheet is a flowsheet used to record
each medication administered during the observation
period and to tally each interruption observed during
the medication pass. Data collectors used the Medica-
tion Administration Accuracy Observation Code Sheet
to record each medication administered, including the
medication name, dose, route, and the time the medica-
tion was administered to the patient. Data collectors
were trained to record the reason for all interruptions
observed by using a free-text, narrative approach. The
project team planned to review the reasons for interrup-
tions after completion of the project and based on post-
hoc analysis, develop a scheme for categorizing the
sources of interruptions.
The Medication Administration Accuracy Record
Review Worksheet is a flowsheet used to identify
medication errors retrospectively by comparing medica-
tions administered during the observation period with
scheduled medication orders on the electronic medica-
tion administration record for the same time period.
Figure 2 Timeline for the Nurses Uninterrupted Passing Medications Safely (NUPASS) project’s pilot practice change.
Abbreviation: AACN, American Association of Critical-Care Nurses.
Attended AACN National
Teaching Institute, Chicago, Ilinois
(5/2009)
Measured % of interruptions and
medication errors after NUPASS
guideline implemented (12/2010)
Poster presentation at
AACN National
Teaching Institute, Boston,
Massachusetts (5/2012)
Measured % of interruptions and
medication errors before
NUPASS guideline
implemented (7/2009)
Pilot study (6/2009)
February
2010
November
2009
August
2011
November
2011
February
20
12
May
2012
February
2011
August
2009
May
2009
November
2010
May
2010
NUPASS guidelines
implemented (2/2010)
Initial internal presentation
of results (6/2011)
Remedial education for
intervention units (8/2010)
Analysis and interpretation
of results (5/2011)
Completed internal
presentation of results
(9/2011)
May
2011
August
2010
Table 4 Nurses Uninterrupted Passing Medications Safely (NUPASS) pilot practice change: operational definitions
Term
Interruption
Avoidable interruptions
Unavoidable interruptions
Medication error
Medication pass
Medication administration process
Definition
An event that halts the process of administering medication, causing the nurse to stop
the task of carrying out a step in the medication administration process and then return
to the medication administration process following disruption by another task or event.
Situations that could be managed by other staff members without risk of patient harm
while the nurse was administering medications. Examples include phone messages from
family members, responding to call lights, and nonemergent communication with staff in
other disciplines.
Situations that required immediate action by the nurse to maintain patient safety. Examples
include acute changes in patients’ status, responding to critical laboratory values, and
verifying and accessing information that may have a critical effect on patients’ outcomes
(eg, a question regarding the exact time a continuous intravenous infusion of heparin was
stopped before proceeding with a scheduled lumbar puncture).
A medication administered to the patient differently than ordered by the physician.
Administration of all medications to a single patient during a scheduled, peak administration time.
The process of administering medications, including medication preparation, administration,
and documentation.
30 CriticalCareNurse Vol 36, No. 4, AUGUST 2016 www.ccnonline.org
Following the observed medication passes, data col-
lectors used the Medication Administration Accuracy
Record Review Worksheet to reconcile the electronic
medication orders with the medications actually admin-
istered to the patients to identify medication errors.
The number and type of medication errors identified
were recorded on the data collection tool, including
wrong drug, dose, form, route, and technique and
omission of drug dose errors.
Communication Strategies
Once baseline data collection was complete on all 3
units, the project team trained the PCCU1 and PCCU2
nursing staff how to implement the NUPASS guidelines.
Staff members were trained to use communication scripts
to respond to nonemergent requests when nurses were
passing medications. The communication script simply
stated, “For the safety of our patients, the nurses are not
interrupted while passing medications. Is there some-
thing I can help you with?” Use of the phrase “for the
safety of our patients” was essential to avoid misconcep-
tions that the nurse was just “too busy” to speak to them.
The unit secretary managed most communication with
visitors and requests for clerical assistance from physi-
cians and other health care providers while the charge
nurse was responsible for addressing patient care
issues with phy-
sicians and
other care pro-
viders. The
nursing staff
was provided with operational definitions of emergen-
cies as part of the NUPASS guidelines; however, because
no guidelines address all situations, the members of the
nursing staff were coached to consider if a safety concern
existed before deciding whether or not to interrupt a
nurse during a medication pass.
The nurses and PCAs coordinated patient care
activities by alternating hourly patient care rounds to
ensure that the timing of nursing rounds corresponded
to the peak times for administering scheduled medications.
Purposeful, hourly rounding has been demonstrated to
decrease patients’ use of call lights and was a best prac-
tice established on the PCCUs before the pilot project
change.23 However, as part of the pilot practice change,
nurses wore a yellow safety sash during scheduled, peak
medication administration times as a visible sign that
they were passing medications and were not to be dis-
turbed. Before beginning the medication pass, nurses also
placed a colored magnet next to their name on the assign-
ment board to alert other care providers that they were in
the process of passing medications. Because the PCCU
assignment boards were in clear view from the centralized
nursing stations, this tactic provided another visible sign
to alert others of the medication pass. Once nurses were
done administering medications, they removed their yel-
low safety sash, picked up their docked phone, removed
the magnet from the assignment board, and checked with
the charge nurse for any logged messages or updates.
Educational Strategies
Unit staff, physicians, and other care providers hospital-
wide were educated on the pilot practice change, includ-
ing the purpose of the project and instructions for
communicating and coordinating care during scheduled,
peak medication administration times. Care providers
from numerous departments (pharmacy, rehabilitation,
nutrition, cardiodiagnostics, emergency, and transpor-
tation service) were educated in 6 months. Education
strategies included staff newsletters tailored to specific
departments, poster presentations, unit-based in-service
training programs, and presentations at scheduled staff
and physician meetings. Upon admission to PCCU1
and PCCU2, a patient-specific newsletter (Table 5) was
used to educate patients and their families about the
pilot project change.
Results
During the pilot practice change, 130 medication
passes were observed on the 3 PCCUs, including 64
medication passes before and 66 medication passes after
guideline implementation. During the 130 medication
passes, nurses were observed administering 631 medica-
tions: 316 medications before and 315 after guideline
implementation. The mean number of medications
administered per patient was 4.10, and the mean dura-
tion of medication passes was 11.69 minutes. Neither
the mean number of medication doses nor the duration
of medication passes differed significantly between units
before or after guideline implementation.
Interruptions
To answer the first question, the percentage of inter-
ruptions decreased significantly in 1 of the 3 PCCUs after
The project team staff nurses collected
all data and observed medication
passes on PCCUs other than their own.
www.ccnonline.org CriticalCareNurse Vol 36, No. 4, AUGUST 2016 31
implementation of the NUPASS guidelines. Interruptions
decreased from 23% to 4% (P < .001) in PCCU1 after imple-
mentation of the NUPASS guidelines. In comparison,
the percentage of interruptions did not change signifi-
cantly in PCCU2, and although the change was not sta-
tistically significant, the percentage increased in PCCU3
after guideline implementation (Table 6). Based on post-
hoc analysis, interruptions were categorized in 2 different
ways: (1) source of the interruption and (2) avoidable
versus unavoidable interruptions.
Four main sources of interruptions were identified:
(1) patient-related, (2) phone calls, (3) verbal (face-to-face
interaction), and (4) unavailability of resources (Figure 3).
Most of the decrease in interruptions after guideline
implementation was due to a 48% reduction in phone calls.
The second largest source of interruptions both before
and after implementation of the NUPASS guidelines
was the unavailability of resources. Of these, 85% were
because the nurse had to stop and get water or a cup
for the patient before administering medications.
In comparison, missing equipment and other supplies
accounted for only 15% of the interruptions in this cate-
gory. The majority of phone calls and verbal (face-to-face)
interruptions were related to patient care activities
including requests from patients, unit personnel, and
other care providers. Interruptions by physicians during
the pilot practice change accounted for only 7% of the
total interruptions. Patient-related sources of interruptions
Table 5 Patient medication safety newsletter
You may hear today:
“For the safety of our patients, we do not interrupt the nurses while they are administering medications. Is there something I can
assist you with?”
A team of nurses is conducting a project to improve patient safety. The purpose of the project is to increase patient safety by
limiting interruptions during medication administration.
Why is this project important? Numerous studies suggest that interruptions during medication administration contribute to
medication errors.
How are interruptions limited when the nurses are administering medications? Nurses will not take phone calls or respond
to inquiries from others including nursing staff, therapists, physicians, patients, and families when they are administering
medications EXCEPT for emergencies during these times:
8 to 10 AM
8 to 10 PM
5 to 7 AM
How will I know when the nurse is administering medications?
Nurses will wear a yellow safety sash to signify that they are administering medications and are not to be interrupted. Limiting inter-
ruptions allows the nurses to keep their attention focused on medication administration and the needs of the each patient who is
receiving medications.
What if I need to communicate with my nurse?
• The phone numbers of your nurse and patient care assistant (“PCA”) are posted on your communication board. You can call them
directly to avoid waiting for your call light to be answered.
• When your nurse is administering medications, his/her calls will be automatically forwarded to the front desk for further assistance.
• The nurse and the PCA take turns rounding at your bedside hourly to offer assistance so that your needs are met promptly.
• If you need help to the bathroom, with bathing, or need something to drink or eat, you can call your PCA.
Who can I talk to if I have more questions about the project? Your nurse will be able to answer most questions. Please also feel
free to direct any questions or comments to the Manager or Advanced Practice Nurse during their daily rounds. This project is a
team effort, and we need your help and support to make it a success!
Thank you from the project team!
Table 6 Interruptions before and after Nurses
Uninterrupted Passing Medications Safely (NUPASS) guide-
lines were implemented
Progressive
cardiac care unit
(PCCU)
PCCU1
(intervention unit)
PCCU2
(intervention unit)
PCCU3
(comparison unit)
Before
NUPASS
22/95 (23%)
25/118 (21%)
10/103 (10%)
After
NUPASS
5/113 (4%)
22/99 (22%)
15/103 (15%)
P
<.001
.46
.24
32 CriticalCareNurse Vol 36, No. 4, AUGUST 2016 www.ccnonline.org
did not differ before or after the implementation of the
NUPASS guidelines.
Avoidable interruptions decreased from 18 to 3 (83%)
in PCCU1 and from 19 to 9 (53%) in PCCU2 while avoid-
able interruptions in PCCU3 increased from 7 to 12
(71%) after implementation of the NUPASS guidelines
(Figure 4). Although PCCU2 did not show a statistically
significant decrease in the total percentage of interrup-
tions following implementation of the NUPASS guidelines,
the unit was successful in decreasing avoidable interrup-
tions by more than half. Unavoidable interruptions
decreased from 4 to 2 (50%) in PCCU1, increased from 6
to 14 (133%) in PCCU2 and increased from 1 to 2 (100%)
in PCCU3 after implementation of the NUPASS guidelines.
Medication Errors
To answer the second question, the percentage of
medication errors decreased in all 3 PCCUs after imple-
mentation of the NUPASS guidelines (Table 7). A statis-
tically significant decrease in the percentage of medication
errors was found in 1 of the 2 intervention units and in
the comparison unit. The percentage of medication
errors in PCCU1 decreased from 11% to 3% after the
guidelines were implemented (P = .02). Although the
percentage of medication errors in the second interven-
tion unit (PCCU2) decreased from 2% to 1%, the number
of observations conducted was not powered to demon-
strate a statistically significant change between such low
percentages of medication errors. An unanticipated find-
ing was a significant decrease in the percentage of medi-
cation errors (P = .01) in the comparison unit (PCCU3).
Discussion
Interruptions
Consistent with the findings of numerous pub-
lished studies, nurses observed during the pilot practice
change were frequently interrupted during medication
administration.6-8,11,12 In addition, results of the pilot
practice change support earlier reports that the majority
of interruptions during medication administration are
avoidable and may lead to adverse consequences for
patients.16,31 The greatest impact of implementing the
NUPASS guidelines was the significant decrease in avoid-
able interruptions, particularly those related to phone
Di i
Table 7 Medication errors before and after Nurses
Uninterrupted Passing Medications Safely (NUPASS)
guidelines were implemented
Progressive
cardiac care unit
(PCCU)
PCCU1
(intervention unit)
PCCU2
(intervention unit)
PCCU3
(comparison unit)
Before
NUPASS
10/95 (11%)
2/118 (2%)
9/103 (9%)
After
NUPASS
3/113 (3%)
1/99 (1%)
1/103 (1%)
P
.02
.57
.01
did diff b f f h i l i f h
Figure 3 Number of interruptions by source before and
after Nurses Uninterrupted Passing Medications Safely
(NUPASS) project.
N
o.
o
f i
nt
er
ru
pt
io
ns
Source
Patient
related
Before NUPASS After NUPASS
Phone
calls
Verbal UnknownResource
unavailable
25
20
15
10
5
0
Figure 4 Avoidable and unavoidable interruptions before
and after Nurses Uninterrupted Passing Medications
Safely (NUPASS) project.
N
o.
o
f i
nt
er
ru
pt
io
ns
Progressive cardiac care unit (PCCU)
PCCU1 PCCU2 PCCU3
Avoidable before NUPASS
Avoidable after NUPASS
Unavoidable before NUPASS
Unavoidable after NUPASS
18
16
14
12
20
10
8
6
4
2
0
www.ccnonline.org CriticalCareNurse Vol 36, No. 4, AUGUST 2016 33
calls. Successfully decreasing interruptions related to
phone calls was highly dependent on teamwork and
highlights the important role of support staff in priori-
tizing and managing phone calls during peak scheduled
medication administration times.
An important paradigm shift for PCCU nurses was
to assume accountability for interruptions, including
avoiding social chatter in the medication room and dele-
gating or deferring tasks when appropriate to main-
tain a concentrated focus on medication administration.
The pilot project team identified differences in unit cul-
ture, workflow demands throughout the 24-hour period,
visibility of leadership, and informal leadership support
on each shift as factors that may have influenced nurs-
ing staff buy-in and adherence to the NUPASS guidelines.
Adherence to the guidelines by physicians, other care
providers, and patients was greatly enhanced by educa-
tion and the use of key messages. The most important
message for gaining cooperation and support from phy-
sicians was that the practice change was to help “manage”
rather than limit communication among care providers.
The responses of patients and their families were
overwhelmingly positive when the pilot practice change
was introduced, and they often shared how impressed
they were that the staff took the patients’ safety so seri-
ously. However, the fact that the number of patient-
related interruptions remained the same before and
after implementation of the NUPASS guidelines sug-
gests the need to reinforce patient education about the
pilot project change throughout the hospital stay such as
signage in the patients’ rooms and verbal reminders.
Although no clinically significant difference was found
in unavoidable interruptions before and after implemen-
tation of the NUPASS guidelines in PCCU1 or PCCU3, a
large increase in unavoidable interruptions occurred in
PCCU2 after guideline implementation; that increase
was attributed to orientation and training of newly hired
nurses during this period.
Medication Errors
It is not clear why the percentage of medication
errors in PCCU2 was lower than in the other 2 units at
baseline. The only observable difference between units
was that PCCU2 has 2 centralized medication rooms
compared with only 1 such room on the other 2 PCCUs.
In addition, the finding that the percentage of medica-
tion errors decreased significantly after guideline
implementation in the comparison unit (PCCU3), inde-
pendent of the percentage of interruptions, highlights
that numerous factors besides interruptions affect
patient safety outcomes.
Sustainability of the Pilot Practice Change
The Institute of Medicine recommends that nurses
be observed periodically to measure actual medication
errors rather than relying completely on voluntary
reporting of medication errors.2 Observation methods
to measure medication errors are useful for overcoming
pitfalls of traditional event reporting, including underre-
porting of errors.32-35 However, direct observation to
measure interruptions and medication errors is time-
and resource-intensive because it requires trained data
collectors and coordination of data collecting activities.
A novel quality improvement approach used at Stanford
Health Care for ongoing measurement of interruptions
and medication errors shared by Elisa E. Nguyen (e-mail
communication, May 22, 2015) is to observe nurses admin-
istering medications as part of regularly scheduled hos-
pital prevalence
studies. Regard-
less of the method
used for collecting
interruption and
medication error
data, ongoing monitoring for quality improvement and
regular, timely feedback to nursing staff regarding mea-
sured outcomes is essential to promote a culture of safety
and sustain results in high-reliability organizations.
After the official project was completed, the
NUPASS project team was not able to continue the
quality improvement monitoring activities to evaluate
the sustainability of the outcomes associated with the
pilot practice change because of time constraints,
nursing staff turnover, and lack of funding. Lack of a
sustainability plan for this project resulted in a drift
back to former practice and is consistent with the find-
ings of Freeman and colleagues,17 who evaluated the
use of a similar set of strategies to limit interruptions in
a single progressive care unit. However, in July 2014, a
modified version of the pilot practice change was imple-
mented in all patient care units as a best practice with
the leadership support of the medical center’s chief nurse
executive. A major change in the guidelines is that the
yellow safety sash has been replaced by a hand-held
Decreasing interruptions was
highly dependent on teamwork
and highlights the important role
of support staff.
34 CriticalCareNurse Vol 36, No. 4, AUGUST 2016 www.ccnonline.org
bar-code scanner as a visible sign that the nurse is
administering medications and is not to be disturbed.
Limitations of the Pilot Practice Change
Although approximately one-third of the PCCU
nurses participated in the project, use of a convenience
sample of nurses limits the representativeness of the
sample. Second, observations were limited to 3 specialty
units at a single site, preventing generalization of the
findings to other patient populations and health care
settings. Third, because the nurses were aware that they
were being observed, they may have followed adminis-
tration safety practices more consistently, leading to
fewer medication errors (Hawthorne effect). Finally,
the comparison unit (PCCU3) was restructured after
the baseline data were collected for the pilot practice
change. The restructuring involved cohorting cardio-
vascular surgical patients at a lower nurse to patient
ratio; both of these factors limit the use of PCCU3 as
a comparison unit.
Last, for the purposes of this project, the definition
of medication errors was limited to administering medi-
cations as ordered by the physician. However, progres-
sive care nurses continuously make clinical judgments
about the appropriateness of carrying out medication
orders. These
judgments are
based on the
patient’s clini-
cal status,
relevant labo-
ratory data,
and contraindications related to risks of complications
associated with diagnostic and interventional proce-
dures. The critical thinking and decision-making pro-
cesses involved in making these judgments represent
important monitoring and surveillance activities nurses
use to keep patients safe regardless of the prescribed
medication order.
Conclusions
Results of the NUPASS pilot practice change demon-
strate that using evidence-based strategies to limit inter-
ruptions during medication administration in the
progressive cardiac care setting decreases avoidable
interruptions and promotes patient safety. Recognizing
medication administration as a high-risk activity is
critical to transforming the culture and engaging nursing
staff to promote the kind of teamwork necessary to limit
avoidable interruptions during medication administra-
tion. In this pilot practice change, we evaluated the
impact of limiting interruptions during medication
administration during scheduled, peak administration
times. The impact of limiting interruptions on medica-
tion errors during unscheduled administration of medi-
cations including as-needed medications and initiation
and titration of high-risk intravenous infusions (eg,
antiarrhythmic and inotropic agents) administered in
the progressive care setting warrants further study.
Although no “magic bullet” is available to prevent
medication administration errors, the outcomes of this
project support the use of evidence-based strategies to
limit interruptions during medication administration
as part of a comprehensive medication safety program.
Bedside nurses have little control over the physical lay-
out of the patient care unit, the nurse to patient ratio,
or access to technological advances to prevent medica-
tion errors; however, they can successfully affect the work
environment to promote patient safety with little or no
cost to the organization by adopting evidence-based
strategies to limit work interruptions during high-risk
activities such as medication administration. ���
Acknowledgments
The authors thank project team members Dawn Hart, RN, BSN, and Sue Glavin,
RN, MSN, FNP, ANCC-BC, for their dedication and commitment to the project,
Wendy Tuzik Micek, RN, PhD, NEA-BC, and Nancy Gaziano, BA, for their editorial
assistance, and Susan Massatt, RN, MA, CCRN, NEA-BC, and Lynn Hennessy, RN,
MS, MBA, NE, for their administrative support.
Financial Disclosures
None reported.
Now that you’ve read the article, create or contribute to an online discussion about
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to comment on. In the full-text or PDF view of the article, click “Responses” in the
middle column and then “Submit a response.”
d tmore
To learn more about patient safety in the critical care setting, read
“Safety Culture in Australian Intensive Care Units: Establishing a
Baseline for Quality Improvement” by Chaboyer et al in the American
Journal of Critical Care, March 2013;22:93-102. Available at www
.ajcconline.org.
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2. Institute of Medicine. Action agenda for health care organizations. In:
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Medication Errors: Quality Chasm Series. Washington, DC: National
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An important paradigm shift for PCCU
nurses was to assume accountability
for interruptions, avoiding social
chatter in the medication room and
delegating or deferring tasks when
appropriate.
www.ccnonline.org CriticalCareNurse Vol 36, No. 4, AUGUST 2016 35
3. Westbrook JI, Woods A, Rob MI, Dunsmuir WT, Day RO. Association
of interruptions with an increased risk and severity of medication
administration errors. Arch Intern Med. 2010;170(8):683-690.
4. Potter P, Wolf L, Boxerman S, Grayson D. Understanding the cognitive
work of nursing in the acute care environment. J Nurs Adm. 2005;
35(7-8):327-335.
5. Kalisch BJ, Aebersold M. Interruptions and multitasking in nursing
care. Jt Comm J Qual Patient Saf. 2010;36(3):126-132.
6. Kreckler S, Catcchople K, Bottomley M, Handa A, McCulloch P. Inter-
ruptions during drug rounds: an observational study. Br J Nurs. 2008;
17(21):1326-1330.
7. Biron AD, Lavoie-Tremblay M, Loiselle CG. Characteristics of work
interruptions during medication administration. J Nurs Scholarsh. 2009;
41(4):330-336.
8. Palese A, Sartor A, Costaperaria G, Bresadola V. Interruptions during
nurses’ drug rounds in surgical wards: observational study. J Nurs Manag.
2009;17(2):185-192.
9. Cornell P, Riordan M. Barriers to critical thinking: workflow interruptions
and task switching among nurses. J Nurs Admin. 2011;41(10):407-414.
10. Clark AP, Flanders S. Interruptions and medication errors. Clin Nurse
Spec. 2012;26(5):239-243.
11. Eisenhower LA, Hurley AC, Dolan N. Nurses’ reported thinking during
medication administration. J Nurs Scholarsh. 2007;39(1):82-87.
12. Relihan E, O’Brien V, O’Hara S, Sike B. The impact of interventions to
reduce interruptions and distractions to nurses during mediation
administration. Qual Saf Health Care. 2010;19(5):52-57.
13. Biron AD, Loiselle CG, Lavoie-Tremblay M. Work interruptions and
their contributions to medication administration errors: an evidence
review. Worldviews Evid Based Nurs. 2009;6(2):70-86.
14. Rivera J, Karsh BT. Interruptions and distractions in healthcare: review
and reappraisal. Qual Saf Health Care. 2010;19(4):304-312.
15. Tomietto M, Sartor A, Mazzocoli E, Palese A. Paradoxical effects of a
hospital-based, multi-intervention programme aimed at reducing medi-
cation round interruptions. J Nurs Manag. 2012;20(3):335-343.
16. Buchini S, Quattrin R. Avoidable interruptions during drug administra-
tion in an intensive rehabilitation ward: improvement project. J Nurs
Manag. 2012;20(3):326-334.
17. Freeman R, McKee S, Lee-Lehner B, Pesenecker J. Reducing interruptions
to improve patient safety. J Nurs Care Qual. 2013;28(2):176-185.
18. Yoder M, Schadewald D, Dietrich K. The effect of a safe zone on nurse
interruptions, distractions, and medication administration errors. J Infus
Nurs. 2015;38(2):140-151.
19. Popescu A, Currey J, Botti M. Multifactorial influences on and deviations
from medication administration safety and quality in the acute medical/
surgical context. Worldviews Evid Based Nurse. 2011;8(11):15-24.
20. Hedberg B, Larsson US. Environmental elements affecting the decision-
making process in nursing practice. J Clin Nurs. 2004;13(3):316-324.
21. Raban MZ, Westbrook JI. Are interventions to reduce interruptions and
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25. Nguyen EE, Connolly PM, Wong V. Medication safety initiative in
reducing medication errors. J Nurs Care Qual. 2010;25(3):224-230.
26. Williams T, King, MW, Thompson JA, Champagne MT. Implementing
evidence-based medication safety interventions on a progressive care
unit. Am J Nurs. 2014;114(11):53-62.
27. Anthony K, Wiencek C, Bauer C, Daly B, Anthony MK. No interruptions
please: impact of a no interruption zone on medication safety in inten-
sive care units. Crit Care Nurs. 2010;30(3):21-29.
28. Kliger J, Blegen MA, Gootee D, O’Neil E. Empowering frontline nurses:
a structured intervention enables nurses to improve medication admin-
istration accuracy. Jt Comm J Qual Patient Saf. 2009;35(12):604-612.
29. Hopkinson SG, Jennings BM. Interruptions during nurses’ work: a
state-of-the-science review. Res Nurs Health. 2013;36(1):38-53.
30. Titler MG, Klieber C, Steelman VJ, et al. The Iowa model of evidence-
based practice to promote quality care. Crit Care Nurs Clin North Am.
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ing to interruptions to nurses’ work and related outcomes. J Nurs
Manag. 2010;18(8):1040-1047.
32. Flynn EA, Barker KN, Pepper GA, Bates DW, Mikeal RL. Comparison of
methods for detecting medication errors in 36 hospitals and
skilled-nursing facilities. Am J Health-Sys Pharm. 2002;59(5):436-445.
33. Ulamino VM, O’Leary-Kelly C, Connolly PM. Nurses’ perception of
causes of medication errors and barriers to reporting. J Nurs Care Qual.
2007;22(1):28-33.
34. Brady AM, Malone AM, Fleming S. A literature review of the individual
and systems factors that contribute to medication errors in nursing
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Running head:
TOPIC SEARCH STRATEGY 2
TOPIC SEARCH STRATEGY 2
Topic Search Strategy
Clinical Question
Medical errors are a serious healthcare issue, which is a leading cause of death in the US. According to Pham et al. (2012), about 98,000 deaths that occur in the Us every year is as a result of medical errors in the healthcare settings. The causes of this problem are difficult to uncover, and when they are found, it is also difficult to provide a solution that minimizes its recurrence. Nurses play a crucial role in enhancing patient safety through monitoring and interception of medical errors that may cause harm to the patients. The most common forms of medical errors reported occur in the process of medication administration, and they include documenting and monitoring patient’s condition, prescription, dispensing, and transcription errors (Hayes et al., 2015). Medication administration is prone to medical errors, and interruptions in this process increase the likelihood of occurrence of errors. Interruptions lead to errors that increase the risk of patient harm, the length of hospital stay, and healthcare costs; thus, there is a need for safety intervention strategies to reduce interruptions.
Studies have revealed that nurses have little time to pay attention to medication administration because of frequent and short interruptions. According to Flynn et al. (2016), the common source of interruption among the nursing staff is seeking assistance or information about patient care from other healthcare providers. Other forms of interruptions include frequent phone calls, conversations unrelated to medications, and inaccessible medical supplies and equipment. Besides, Hayes et al. (2015) state that nurses engage in medication administration for about 16 to 40% of their time. Thus, the way interruptions are managed in the medication administration process impacts the ability of the nurses to deliver safe and effective care to the patients. On the other hand, the study by Cheragi et al. (2013) indicated that 64.55% of the nurses reported medication errors, while 31.37% of them are on the verge of a medication error. The study also reported a mean incidence of medication errors to be 7.4 for each nurse in three months. The findings from these studies indicate that medication errors often occur in the nursing practice due to interruptions and suggest the need to utilize safety interventions to limit interruptions, especially during medication administration.
Elimination of medication errors was the source of the PICO question, “For the nurses taking care of patients in healthcare settings, how can safety interventions as compared to no intervention reduce medication errors?” This paper aims at finding out how safety interventions can help in reducing medication errors, which is common among nurses during medication administration.
Search Strategy
The strategy utilized when looking for an article was to get an article that has a high level of evidence and relevant to the PICO question. Using the Chamberlain University Library, I search through various databases, including PubMed and Medline. The search was achieved by turning the PICO question into a research topic. For instance, the research topic used is “Safety interventions to reduce medication errors in nursing practice.” The search terms that I used to search for the article that answers the PICO question include medication errors, safety interventions, nursing errors in healthcare settings, and medication administration. The initial search using the key words gave 543 results. I did an advanced search by putting limits on my search, such as searching for articles published from 2015 to 2020, having full text available, and peer-reviewed. This criterion gave me a more narrowed search that is appropriate for this assignment and gave 17 results. From the 17 results, I chose one article, which is a study by Flynn et al. (2016). This article has a manageable number of pages; hence, information can be extracted within a short time. Also, the article is rich in information that helps answer the PICO question.
Level of Evidence
The type of research question being asked is a prognosis question. A prognosis question determines a course over time (safety intervention) and provides a guess to the expected outcome (reduce the medication errors). The question is asking the effectiveness of safety interventions in the reduction of medication errors in nursing care in healthcare settings. Various safety interventions can be taken by nurses to reduce medication errors. This question can be answered through cohort studies because it involves participants making observations before coming up with an outcome in question. Flynn et al. (2016) noted that medication errors occur in medication administration as a result of interruptions, and the implementation of evidence-based strategies aiming to reduce interruptions will promote patient safety. This is a mixed-method study conducted through direct observation of nurses on two progressive cardiac care units. The quantitative data gathered in the research provide accurate evidence on the incidences of medication errors and the effectiveness of the safety interventions. Based on the evidence hierarchy, this study by Flynn et al. (2016) provides level 5 evidence, and thus, they are becoming more reliable.
References
Cheragi, M. A., Manoocheri, H., Mohammadnejad, E., & Ehsani, S. R. (2013). Types and causes of medication errors from nurse’s viewpoint. Iranian Journal of Nursing and Midwifery Research, 18(3), 228–231. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748543/#:~:text=While%20a%20great%20number%20of
Flynn, F., Evanish, J. Q., Fernald, J. M., Hutchinson, D. E., & Lefaiver, C. (2016). Progressive Care Nurses Improving Patient Safety by Limiting Interruptions During Medication Administration. Critical Care Nurse, 36(4), 19–35. https://doi.org/10.4037/ccn2016498
Hayes, C., Jackson, D., Davidson, P. M., & Power, T. (2015). Medication errors in hospitals: a literature review of disruptions to nursing practice during medication administration. Journal of Clinical Nursing, 24(21–22), 3063–3076. https://doi.org/10.1111/jocn.12944
Pham, J. C., Aswani, M. S., Rosen, M., Lee, H., Huddle, M., Weeks, K., & Pronovost, P. J. (2012). Reducing Medical Errors and Adverse Events. Annual Review of Medicine, 63(1), 447–463. https://doi.org/10.1146/annurev-med-061410-121352
Cover
©2
0
16 American Association of Critical-Care Nurses doi: http://dx.doi.org/10.4037/ccn201649
8
CE 1.0 hour
Fran Flynn, APRN, MS, BC-CNS
Julie Q. Evanish, RN, BS, PCCN
Josephine M. Fernald, RN, BSN, PCCN
Dawn E. Hutchinson, RN, BSN, PCCN
Cheryl Lefaiver, RN, PhD, CCRP
Progressive Care Nurses
Improving Patient Safety by
Limiting Interruptions During
Medication Administration
BACKGROUND Because of the high frequency of interruptions during medication administration, the
effectiveness of strategies to limit interruptions during medication administration has been evaluated in
numerous quality improvement initiatives in an effort to reduce medication administration errors.
OBJECTIVES To evaluate the effectiveness of
evidence-based strategies to limit interruptions during
scheduled, peak medication administration times in 3 progressive cardiac care units (PCCUs). A sec-
ondary aim of the project was to evaluate the impact of limiting interruptions on medication errors.
METHODS The percentages of interruptions and medication errors before and after implementation of
evidence-based strategies to limit interruptions were measured by using direct observations of nurses
on 2 PCCUs. Nurses in a third PCCU served as a comparison group.
RESULTS Interruptions (P < .001) and medication errors (P = .02) decreased significantly in 1 PCCU after
implementation of evidence-based strategies to limit interruptions. Avoidable interruptions decreased
83% in PCCU1 and 53% in PCCU2 after implementation of the evidence-based strategies.
CONCLUSIONS Implementation of evidence-based strategies to limit interruptions in PCCUs decreases
avoidable interruptions and promotes patient safety. (Critical Care Nurse. 2016;36[4]:19-35)
This article has been designated for CE contact hour(s). The evaluation tests your knowledge of the following objectives:
1. Describe similarities between the principles of the sterile cockpit concept used in the aviation industry and the Nurses Uninterrupted Passing Medications Safely
(NUPASS) guidelines to promote safety
2. Discuss the current evidence supporting use of interruption limiting strategies to reduce medication administration errors in the acute care setting
3. Implement evidence-based strategies to limit interruptions during medication administration
To complete evaluation for CE contact hour(s) for test #C1642, visit www.ccnonline.org and click the “CE Articles” button. No CE test fee for AACN members.
This test expires on August 1, 2019.
The American Association of Critical-Care Nurses is an accredited provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on
Accreditation. AACN has been approved as a provider of continuing education in nursing by the State Boards of Registered Nursing of California (#01036) and Louisiana (#LSBN12).
N
urses play a critical role in promoting patient safety through surveillance and inter-
ception of errors that cause patient harm as hospitals and health care systems strive
to become high-reliability organizations.1 The Institute of Medicine estimates that
medication errors result in several thousand deaths annually.2 Interruptions during
complex or high-risk activities such as medication administration increase risk of
www.ccnonline.org CriticalCareNurse Vol 36, No. 4, AUGUST 2016 19
20 CriticalCareNurse Vol 36, No. 4, AUGUST 2016 www.ccnonline.org
Authors
Fran Flynn was the advanced practice nurse on one of the progressive cardiac units at the time of the project and is now the advanced practice
nurse for the inpatient palliative care service, Advocate Christ Medical Center, Oak Lawn, Illinois.
Julie Q. Evanish was a bedside nurse in one of the progressive cardiac units at the time of the project and is now working in the outpatient
pain clinic, Advocate Christ Medical Center.
Josephine M. Fernald was a bedside nurse in one of the progressive cardiac care units at the time of the project and is now working in the
outpatient heart failure clinic, Advocate Christ Medical Center.
Dawn E. Hutchinson was a bedside nurse in a progressive cardiac care unit when the study was done and is now a clinical informatics
specialist, Advocate Christ Medical Center.
Cheryl Lefaiver was the professional nurse researcher for the medical center when the study was done and is now manager of patient-centered
outcomes research for Advocate Center for Pediatric Research, Advocate Christ Medical Center.
Corresponding author: Fran Flynn, APRN, MS, BC-CNS, Advocate Christ Medical Center, 4400 W 95th St, Oak Lawn, IL 60453 (e-mail: fran.flynn@advocatehealth.com).
To purchase electronic or print reprints, contact the American Association of Critical-Care Nurses, 101 Columbia, Aliso Viejo, CA 92656. Phone, (800) 899-1712 or (949)
362-2050 (ext 532); fax, (949) 362-2049; e-mail, reprints@aacn.org.
patient harm, and strategies to reduce interruptions
and manage them appropriately are needed.3 On the
basis of the current evidence, the Institute of Medicine
recommends that organizations adopt strategies to
reduce interruptions during medication administration
as part of a comprehensive medication safety program.
2
The quality improvement project described here
evaluates the impact of adopting evidence-based strate-
gies to limit interruptions during medication adminis-
tration in 2 progressive cardiac care units (PCCUs) at
Advocate Christ Medical Center, a Magnet-designated
tertiary care center in the Midwest. A third PCCU served
as a comparison unit and, therefore, did not adopt the
interruption-limiting strategies. A secondary aim of the
project was to evaluate how limiting interruptions
affected medication errors in this setting.
Background
In a plenary speech at the 2008 National Teaching
Institute, the former president of the American Associa-
tion of Critical-Care Nurses challenged more than 9000
nurses in attendance to avoid multitasking and interrup-
tions when
administering
medications
in order to
prevent medi-
cation errors.
Attendance at this speech was the inspiration for this
project and became the springboard for addressing
existing nursing concerns about interruptions.
Review of the Literature
Observational studies describe the high cognitive
work of nurses coupled with frequent interruptions and
multitasking behaviors during direct patient care activ-
ities in acute care settings.4-8 The work environment is
error-prone, especially during complex or high-risk
activities, because interruptions and multitasking
behaviors create conditions affecting working memory
and attention resources.9,10 Nurses’ cognitive processes
during medication administration are complex and
require a high degree of critical thinking and vigilance
to prevent patient harm.11 Medication administration
is one of the most frequently interrupted nursing
activities,4,6,12 and strategies to limit interruptions are
recommended to improve patient safety.
Studies describing the frequency and characteristics
of interruptions during medication administration show
that nurses have little protected time to focus on medica-
tion administration because of short, frequent interrup-
tions.6-9,12,13 The most common source of interruptions is
interactions with other nursing staff seeking information
or assistance with patient care.13 The frequency of inter-
ruptions by other care providers varied significantly
across studies.13,14 Although they were not the most fre-
quent source of interruptions, phone calls were identi-
fied by nurses as one of the most disruptive sources of
interruptions and one of the most likely sources of inter-
ruptions to be associated with medication errors.8,12
System failures such as missing medications and access
to equipment and supplies were also identified as sources
of interruptions that are potentially avoidable.7,8,12-16
Other avoidable interruptions cited in the literature are
the tendency of nurses to interrupt each other with
conversations unrelated to medication administration7,17-19
while preparing medications and to respond immedi-
ately to requests from others when interrupted.7,15,20
These findings support the idea that interruptions are
an accepted part of nursing practice and suggest the
Attendance at the National Teaching
Institute was the inspiration for this
project and the springboard for
addressing existing nursing concerns
about interruptions.
www.ccnonline.org CriticalCareNurse Vol 36, No. 4, AUGUST 2016 21
need for culture change to limit avoidable interruptions,
especially during complex or high-risk activities such as
medica
tion administration.
Development and testing of strategies to limit inter-
ruptions during the medication administration process
are primarily based on research from the aviation indus-
try. In 1981, the Federal Aviation Authority mandated
use of standard operating procedures to create a sterile
cockpit situation aimed at reducing unsafe working con-
ditions and preventing errors during high-risk activities
such as aircraft takeoff and landing. Essential aspects of
the sterile cockpit concept include eliminating interrup-
tions, prohibiting communication unrelated to critical
tasks, and maximizing teamwork and coordination
during high-risk activities.21,22 The majority of published
clinical initiatives to limit interruptions during medica-
tion administration are nurse-led quality improvement
projects involving implementation of a set of strategies
to limit interruptions (Table 1). The goal of these initia-
tives is to provide nurses with time to remain focused
and undisturbed while preparing and administering
medications. Direct observations of nurses preparing
and administering medications during peak, scheduled
administration times were used to study interruptions
in these quality improvement projects. Results of these
projects demonstrate that implementation of a set of
strategies is effective in limiting interruptions and may
improve patient safety by decreasing medication errors.
To date, 1 study3 examining the direct relationship
between work interruptions and hospital medication
administration errors has been published. Results of this
landmark study demonstrated that the frequency of
interruptions during medication administration increased
the risk of both the number and severity of medication
errors. Table 2 provides a detailed analysis of the litera-
ture regarding cognitive work of nurses and the com-
plexity of the work environment, interruptions during
medication administration, strategies used to limit inter-
ruptions during medication administration, and the
contribution of interruptions to medication errors.
Introduction to the Progressive Cardiac
Care Quality Improvement Project
The PCCU quality improvement project was developed
and implemented on the basis of the work of Nguyen
and colleagues.25 In the quality improvement project
presented here, the project team implemented a set of
evidence-based strategies to limit interruptions during
scheduled, peak medication administration times in
the progressive cardiac care setting. The project team
embedded the interruption strategies into practice guide-
lines to promote communication, coordination of care,
and teamwork during medication administration. The
guidelines are referred to as the “NUPASS guidelines,” on
the basis of the project’s name: Nurses Uninterrupted
Passing Medications Safely (Table 3).
The project’s conceptual framework is
based on the
medical center’s Evidence-Based Practice (EBP) Model
(Figure 1). The EBP model was adopted and modified
on the basis of the Iowa model.30 Using the EBP model
as a guide, the project team initiated a pilot practice
change based on the current evidence supporting use
of strategies to limit interruptions during medication
administration. The pilot practice change was designed
to answer 2 questions: (1) Does implementation of the
NUPASS guidelines decrease interruptions during medi-
cation administration? and (2) Do medication errors
decrease following implementation of NUPASS guide-
lines? The pilot practice change was conducted on 2 of
the 3 PCCUs; PCCU1 and PCCU2 were the intervention
units that implemented the NUPASS guidelines, and
PCCU3 served as
a comparison unit.
Patients cared for in the high-acuity PCCUs typically
included patients who required invasive diagnostic and
interventional cardiovascular procedures, cardiovascular
surgery, and arrhythmia management. Common medi-
cal diagnoses included acute coronary syndrome, heart
Table 1 Evidence-based strategies to limit
interruptions during medication administration
1. Hourly patient rounds23
2. Scripts for triage of phone calls17,22,24-26
3. Protected time for passing medications without
interruptions17,22,
2
5
4. Signage to remind staff to limit interruptions12,17,22,24-26
5. “No interruption zone”/“quiet zone” established in
medication rooms17,24-27
6. Phone calls to nurses limited during medication
administration17,25
7. Nurses don visible wear as a nonverbal cue that they
are administering medications and are not to be
disturbed12,17,22,26
8. Distribution of patient/family education materials about
limiting interruptions during medication administration12,17
22 CriticalCareNurse Vol 36, No. 4, AUGUST 2016 www.ccnonline.org22 C i i lC N
Table 2 Detailed review of the literature
Reference
Potter et al,4 2005
Eisenhower et al,11 2007
Kalisch and Aebersold,5
20
1
0
Cornell and Riordan,9
2011
Kreckler et al,6 2008
Biron et al,7 2009
Palese et al,8 2009
Biron et al,13 2009
Sample/setting
Convenience sample of 7 nurses with
acute care experience and clinical
background
Large, tertiary medical center in the
Midwest
Convenience sample of 40 nurses
working in intermediate medical-
surgical intensive care unit
(M/S ICU) and ante/postpartum unit
Large, tertiary teaching hospital in
the Northeast
Convenience sample of 36 nurses
from 5 M/S units, 1 ICU, and 1
progressive care unit
Seven patient care units in 2
Midwestern hospitals including
an academic medical center and a
community-based teaching hospital
Convenience sample of 19 nurses
from 2 hospitals including 8 nurses
on an M/S unit at a suburban,
acute care hospital and 11 nurses
on a pediatric oncology unit at a
pediatric research hospital in the
United States
Convenience sample of nurses
working on a 37-bed surgical unit
at a teaching hospital in the United
Kingdom
Convenience sample of 18 nurses
working on a medical unit at a
tertiary care teaching hospital in
Quebec
A convenience sample of nurses
working on 7 surgical units across
multiple, similar type hospitals in
Northern Italy
Articles from 1980 to 2008 were
analyzed
Design/procedures
Mixed method ethnographic observa-
tional study combining quantitative
human factor engineering techniques
with summative nurse interviews
Nurses were observed for a total of 48 h
Descriptive study with semistructured
interviews
Observational study
A previously validated instrument
referred to as the “Communication
Observation Tool” was used by 4
trained staff nurses to collect data
For the purpose of this study, both
procedural failures and medication
administration errors were counted
as errors
Observational study limited to nurs-
ing activities outside of the patient’s
room during 85.2 h of observation
Observational study
Thirty-eight medication passes were
observed in 5 weeks
Observational study
Descriptive data included source and
duration of interruptions, nursing
tasks and location during interrup-
tions and strategies used by nurses
to manage interruptions
Mixed-method study combining
observation of nurses during medica-
tion administration followed by nurse
interviews during a 3-month period
Systematic review
Fourteen of 23 studies selected for
analysis reported observation times
and interruption frequencies and
therefore, underwent further analysis
Purpose
Analyze nurses’ cognitive work
and how environmental fac-
tors create disruptions that
pose risk for medical errors
Describe nurses’ thinking
during medication admin-
istration before and after
implementation of bar-code
medication scanning (point-
of-care technology)
Evaluate the type and extent
of work interruptions, multi-
tasking, and errors
Assess the complexity of
nurse workflow and review
its cognitive implications
Determine the time required
by nurses to deal with inter-
ruptions and the nature of
nurses’ work interruptions
(WIs) during medication
administration
Document characteristics of
nurses’ WIs during medi-
cation administration
Examine the frequency and
perceived risk of WIs during
medication administration
Review the evidence on
nurses’ interruption rates,
characteristics of WIs, and
contribution of WIs to medi-
cation administration errors
A. Cognitive work of nurses and complex work environment
B. Interruptions during medication administration
www.ccnonline.org CriticalCareNurse Vol 36, No. 4, AUGUST 2016 23C i i lC N 23
Findings/conclusions
Nurses averaged 9 cognitive shifts per hour or a shift in attention focus once every 6-7 min
The human factor engineer found 5.9 interruptions per hour and the nurse researcher found an average of 3.4 interruptions per hour
Twenty-two percent of interruptions occurred in the medication room during medication preparation, and no attempt was made by
nurses to control sources of the interruptions
Nurses’ constant vigilance to provide the appropriate medication was a common theme found in the content analysis
Nurses’ thinking was categorized into 10 descriptive categories; the only change in thinking after implementing bar-code scanning was
the descriptive category related to checking medications
Key aspects of critical thinking identified included assessment of the patient before and after administration of medications, interpretation
and verification of relevant laboratory data, application of knowledge to specific patient situations, anticipatory problem solving related
to the patient’s expected clinical trajectory and consultation with health care team members to prevent medication errors and adverse
drug events
The mean interruption rate observed at the 2 hospitals was 10 interruptions per hour resulting in a break in task more than 1/3 of the time
Interruptions occurred every 6 minutes for hospital 1 and every 4.5 min for hospital 2; nurses were interrupted during medication
administration 57% and 36% of the time in hospital 1 and hospital 2, respectively
Nurses engaged in multitasking an average of 30% and 40% of the time in hospital 1 and hospital 2, respectively
Significantly more interruptions (P < .001), multitasking (P < .001), and breaks in task (P < .001) occurred in ICUs than in the M/S units
No more errors were found when nurses were interrupted or multitasking vs when nurses were not interrupted or multitasking
More than 2000 tasks were recorded on each unit during 35.7 h of observation on the M/S unit and 49.5 h of observation on the pediatric
oncology unit
The duration of tasks was short with a mean of 62.4 (SD, 127.7) s and 49.5 (SD, 81.6) s on the M/S unit and pediatric oncology unit,
respectively
The reason for switching tasks (self-directed or external) was not discernible
Nurses frequently changed locations when switching tasks
Medication passes were interrupted a mean of 11% of the time
Two-thirds of the medication passes were interrupted with a mean of 2.61 interruptions per medication pass
The 3 most frequent sources of interruptions in descending order were (1) interruptions by the nurse administering medication (self-initiated),
(2) interruptions by physicians, and (3) interruptions by other staff and patients
Phone calls were not the most frequent source of interruption; however, they were found to be significant because of their longer duration
WIs averaged 6.3 per hour (5.2 per hour during medication preparation and 6.8 per hour during medication administration)
WIs were of short duration with a mean of 1 min 32 sec (SD, 2 min)
The most frequent WIs during medication preparation were by nurse colleagues followed by system failures due to missing medication
and equipment
Nurses preparing medications were interrupted by other nurses for personal matters 36% of the time and to exchange verbal reports
22% of the time
The most frequent WIs during medication administration were self-initiated and by patients during direct patient care activities
Nurses handled WIs immediately more than 98% of the time; the proportion of WIs handled immediately was similar during both
medication preparation and administration (98.8% and 97.6%, respectively)
A mean of 1 interruption per 3.2 drugs administered occurred during medication administration
When there was an increased number of drugs per medication pass for a single patient, the number of interruptions increased significantly
(P = .05).
Nurses intervened immediately when interrupted 96% of the time
Nurses perceived interruptions related to management of phone calls to be the highest risk for error during medication administration
Pooled data from 14 studies found WIs occurred at a rate of 6.7 interruptions per hour
The majority of interruptions were self-initiated by nurses administering medications during face-to-face interactions, occurred most
frequently during direct patient care, and were of short duration ranging from 45 sec to 1.2 min
Only 1 nonexperimental study documented the contribution of interruptions to medication errors with evidence of a significant association
(P = .01).
Continued
Table 2 Continued
Reference
Pape,22 2003
Nguyen et al,²5 2009
Anthony et al,27 20
10
Freeman et al,17 2013
Williams et al,26 2014
Sample/setting
Convenience sample of M/S unit
nurses were observed during a
single medication pass for assigned
patients in a 520-bed acute care
hospital in Texas
Forty-five nurses working on a 25-bed
M/S unit at an academic teaching
hospital in Northern California
The project was conducted in
partnership with a larger quality
improvement (QI) initiative spon-
sored by the Integrated Nurse
Leadership Program aimed at
improving patient safety and involved
7 hospitals in the San Francisco Bay28
Convenience sample of medical ICU
and surgical ICU nurses working in
a tertiary academic medical center
in Cleveland, Ohio
Convenience sample of 99 nurses in
a cardiac and thoracic surgical
step-down unit at a large, academic
medical center in the Midwest
Convenience sample of nurses
working in a surgical progressive
care unit (52 before intervention
and 48 after intervention)
Academic medical center in the
southeastern United States
Design/procedures
Quasi-experimental 3-group study
design including a comparison
group and 2 intervention groups
A validated instrument referred to
as the Medication Administration
Distraction Observation Sheet
(MADOS) was used to count
distractions
A longitudinal observational QI
project
One hundred medication passes
were observed before the interven-
tion and at 6 months and 1 year
after the intervention
Observational pilot project
A “no interruption zone” (NIZ) was
created by placing red tape around
all medication preparation areas to
signify that nurses were not to be
disturbed while preparing
medications
The number of interruptions before
and 4 weeks after the NIZ was
implemented were measured
Nurses observed were blinded to the
purpose of the study
Observational QI project.
A modified version of the MADOS
instrument was used to count the
number and type of interruptions
Observational study
Distractions and interruptions were
measured using the MADOS instru-
ment before and 2 months after
implementation of 5 evidence-
based safety strategies including
nursing staff education, use of a
medication safety vest, NIZ in
medication preparation areas,
signage on the unit and patient
rooms, and a resource tool for
scripting responses to interruptions
Purpose
Test the effectiveness of 2
interventions (“focused”
protocol and “medsafe”
protocol) to reduce distrac-
tions during medication
administration in comparison
to usual practice
Determine which distractors
are more predictive of nurses
being distracted during
medication administration
Evaluate whether a safety
initiative referred to as the
“Med Pass Time Out” was
effective and sustainable in
reducing medication
administration errors
Evaluate the effect of a NIZ on
the number of interruptions
during medication preparation
Determine whether implemen-
tation of a set of interventions
would reduce interruptions
during medication adminis-
tration
A secondary project goal was
to reduce medication errors
Interventions implemented
were previously described
in the literature, including
wearing a lighted lanyard
during medication adminis-
tration, triage of phone
calls, creating an NIZ in the
medication preparation
area, signage, and staff and
patient/family education
To evaluate the effectiveness
of implementing 5 evidence-
based safety strategies to
reduce distractions and
interruptions during
medication preparation
C. Strategies to limit interruptions
Findings/conclusions
Significant differences in the mean number of distractions were found between the comparison group and both intervention groups
(P < .001) as well as between the 2 intervention groups (“focused” protocol [P = .01] and “medsafe” protocol [P < .001])
The significant difference between the 2 intervention groups was attributed to use of a visible symbol that the nurse wore during medication
administration (a red vest with the lettering “Medsafe Nurse, Do Not Disturb”)
Conversation accounted for the majority (93%) of the variance in distractions, followed by interruptions by personnel (90%) and loud noises
Uninterrupted time increased from 81% to 99% of the time at 6 months and 1 year after implementation of the “Med Pass Time Out”
Medication errors decreased from 2% to 1% at 6 months and improvement was sustained at 1 year
No statistical analysis
The number of interruptions decreased by 40.9% (from 31.8% to 18.8%) after implementation of the NIZ (P = .03).
The proportion of interruptions initiated by nurses preparing medications (self-initiated interruptions) decreased from 25% to 0%
following implementation of the NIZ
Mean number of interruptions decreased from 3.29 to 1.18 during medication administration
Medication errors decreased by 28 events when compared with the same time period the year before
Patients, nurses, and patients’ family members represented the top 3 sources of interruptions before implementing interventions to
reduce interruptions; 1 month after implementation of the interventions, no interruptions were made by family members
No statistical analysis
Four types of distractions and interruptions decreased significantly after implementation of the safety strategies including those
initiated by (1) physicians, nurse practitioners, and physician assistants (P = .001), (2) phone calls and pages (P = .001), (3) other
personnel (P < .001), and (4) conversations unrelated to medication administration (P = .002)
Total reported adverse drug events decreased from 10 to 4 (60%)
Nurse were not found to be compliant with wearing the safety vest or using the resource tool when responding verbally to interruptions
but were compliant with use of signage and the NIZ when preparing medications
Continued
Table 2 Continued
Reference
Westbrook et al,3 2010
Hopkinson and
Jennings,29 2013
Raban and Westbrook,21
2014
Sample/setting
Convenience sample of 98 nurses
from 6 units at 2 major teaching
hospitals in Sydney, Australia
A total of 31 articles published
between 2001 and 2011 were
selected for analysis, including 12
that specifically examined nurse WIs
during medication administration
Studies were conducted in 7 countries,
including 14 studies conducted in
US acute care facilities
Ten studies meeting inclusion criteria
and published up to September 2012
were analyzed
Eight of the 10 studies were
published in North America
All studies used direct observation
for data collection, but studies were
not limited to the acute care setting
Design/procedures
Observational study
A total of 505 hours of observation
was conducted during an
18-month period
Systematic review
Most studies used a nonexperimental
design and involved direct observa-
tion methods for data collection
Systematic review
Studies included for analysis were
observational studies that reported
quantitative data on interruptions
or medication administration errors
with a pre- and postintervention
design or use of a comparison group
Studies included were not limited to
the acute care setting
Purpose
Examine the direct relation-
ship between WIs and
hospital medication
administration errors
Examine empirical evidence
from studies of nurse WIs
in the acute care setting
Assess evidence of the
effectiveness of interven-
tions aimed at reducing
interruptions during
medication administration
on
interruption and
medication administration
error rates
D. Contributions of interruptions to medication errors
Table 3 Nurses Uninterrupted Passing Medications Safely (NUPASS) guidelines
Before administering medications
1. Nurses update the charge nurse (CN) before administering medications if there are changes in patients’ status that affect
scheduled procedures or transport needs; otherwise, nurses simply place a colored magnet next to their name on the
assignment board (board in clear view at the front desk) to indicate that they are administering medications.
2. Nurses dock their phones just outside the medication room before entering to prepare medications. Docked phones are
programmed to forward all calls to the front desk.
3. Nurses don a yellow safety sash before leaving the medication room to administer medications.
After administering medications
1. Once medication administration is compete, nurses return their yellow safety sash to the medication room, pick up their
docked phone, remove the colored magnet from the assignment board, and check at the front desk for any new messages
recorded on a communication log.
General practice progressive cardiac care unit (PCCU) guidelines
1. Nurses perform hourly rounds on odd hours (corresponds with peak, scheduled medication times). Patient care assistants
(PCAs) perform hourly rounds on even hours.
2. Phone and face-to-face requests by family for patient information are screened for a password in accordance with the medical
centers’ policy for compliance with the Health Insurance Portability and Accountability Act (HIPAA) before contacting the
assigned nurse.
3. Nursing staff use key phrases to respond to nonemergent requests or inquiries: “For the safety of our patients,” we do not
interrupt the nurse while administering medications. Is there something I can help you with?
4. Unit secretaries refer requests/inquiries to the CN only in situations where they cannot triage or manage the communication
themselves.
5. Prespecified peak, scheduled medication administration times for “no interruption” except emergencies: 5 AM-7 AM,
8 AM-10 AM, and 8 PM-10 PM. Emergencies include imminent patient safety concerns, patients’ request for pain medica-
tion, emergency response to cardiac arrhythmia alert, need to communicate information only assigned nurse has specific
knowledge of in a critical event, rapid response, or cardiopulmonary arrest of assigned patient.
6. Signage on closed medication room door reminds staff that medication room is a “quiet zone.”
7. “No interruption zone” (NIZ) outlined on floor in the medication room next to the medication storage/delivery system.
8. “Daily Patient Care Activity Flowsheet”: Day-shift CN receives a brief report on each patient from the assigned nursing staff,
including scheduled procedures and patient transport needs for the next 24 hours before 8 AM daily during “huddle-up.”
This information is logged by the day-shift CN on a structured daily flow sheet and is updated by the evening and night
CNs on the basis of the corresponding shift reports by nursing staff to assist with coordination of patient care activities.
9. “Communication log”: used to document nonurgent messages while nurses are administering medications.
10. Patient/family education tool: written patient/family education provided on admission to help explain the pilot practice change.
www.ccnonline.org CriticalCareNurse Vol 36, No. 4, AUGUST 2016 27
failure, and uncontrolled atrial fibrillation. Patient care
was delivered by nursing staff including registered nurses
and certified nursing assistants referred to as patient care
associates (PCAs). The nurse to patient ratio was 1 to 4
on the day and evening shifts and 1 to 5 on the night shift.
The number of beds on each unit was from 36 to 46, and
the daily patient census was from 34 to 39. Technol-
ogy used to support the medication administration pro-
cess at the time of the pilot practice change included a
centralized medication storage system, computer phy-
sician order entry, and electronic medication administra-
tion record. Bar-code scanning of medications was not
available at the time of the pilot practice change. Geo-
graphic differences in the layout of the PCCUs included
the number of medication rooms and the number of
semiprivate versus private patient rooms. The project team
for the pilot practice change consisted of 5 bedside nurses
from the PCCUs, an advanced practice nurse, and a
nurse researcher.
Methods
Data Collection
The pilot practice change was conducted for 18
months. The baseline percentages of interruptions
and medication errors were measured in July 2009,
and these measures were repeated after implementa-
tion of the NUPASS guidelines in December 2010
(Figure 2). A convenience sample of nurses from each
PCCU was randomly observed during peak, scheduled
medication administration times. Nurses were aware
of being observed during data collection. Data collec-
tors used the following script to explain why they
were conducting observations during medication
administration:
We are conducting a quality improvement
project to identify opportunities to improve
patient safety during medication administra-
tion. All data [are] being collected anony-
mously and [do] not include the identity of
the nurses being observed during medica-
tion administration.
Observations were conducted during prespecified
times (5 AM – 7 AM, 8 AM – 10 AM, and 8 PM – 10 PM). The
number of observations conducted for each prespecified
time was based on the mean number of medications
scheduled during these peak administration times. The
project team staff nurses collected all data and observed
medication passes on PCCUs other than their own.
Two standardized data collection tools referred to as
the Medication Administration Accuracy Observation
f il d t ll d t i l fib ill ti P ti t d h d f i l
Findings/conclusions
Each interruption was associated with a 12.1% increase in procedural failures and a 12.7% increase in medication errors
The frequency of interruptions during medication administration increased the risk of both the number and severity of medication errors
The estimated risk of a major error, defined as an error most likely to cause harm, permanent damage or death, doubled from 2.3%
with no interruption to 4.7% with 4 or more interruptions during administration of scheduled medications to a single patient
The evidence for reducing medication errors by limiting interruptions remains at the level of descriptive research because the majority
of projects were nurse-led QI projects
Interpretation of results was limited because of the different methods used for unit sampling, measuring, and defining interruptions
Five studies had statistically significant changes in the number of interruptions before and after implementation of a set of interventions;
interruptions decreased in 4 studies and increased in 1 study
The 3 studies that measured changes in medication error rates showed reductions, but all 3 studies implemented multiple interventions
besides those aimed at reducing interruptions
Weak evidence of the effectiveness of interventions intended to reduce interruptions and medication error rates exists primarily owing
to the small number of studies, and the lack of robust study design, appropriate statistical analyses, and small sample size
28 CriticalCareNurse Vol 36, No. 4, AUGUST 2016 www.ccnonline.org
Code Sheet and the Medication Administration Accuracy
Record Review Worksheet developed by the California
Nursing Outcomes Coalition (CALNOC) were modified
and adapted for use with written permission of CALNOC
(March 26, 2009). Before implementation of the pilot
practice change, an interrater reliability study involving
30 observations (10 per unit) was conducted to establish
agreement among trained data collectors and resulted
in 96% agreement. Operational definitions used for the
purposes of data collection during the pilot practice
project are listed in Table 4.
During observations, the data collectors were blinded
to the electronic medication orders to prevent confirma-
tion bias. The Medication Administration Accuracy
d h d h d d
Figure 1 Evidence-based practice (EBP) model.
Abbreviations: AHC, Advocate Health Care; APN, advanced practice nurse; IRB, institutional review board; NRC, Nursing Research Committee; PDSA, plan, do, study, act;
PICO, problem or population, intervention, comparison, and outcome.
Iowa Model adapted from Titler et al,30 with permission. ©University of Iowa.
Use the PICO Framework Worksheet (1)
to develop your PICO question.
Conduct Research
IRB Process
Identify Clinical Question/Problem (PICO)
Request to Investigate Practice
Complete Synthesis of
Evidence Worksheet
**Present to Council
(The council will depend
upon the type of project)
Pilot Practice Change
AHC Project Completion and Education
Planning Form (7)
Communicate Change
Monitor and Analyze Outcome Data
Nursing Research
Resource: AHC NRC
IRB Submission &
Review Process (9)
Complete the Practice Investigation Approval Form (2)
to assess a need for change and identify stakeholders.
Meet with librarian and/or APN and use the Evidence Matrix
(3) and Level of Evidence Reference (4) as tools for your
literature search. Critique and synthesize evidence using
the Evidence Synthesis Worksheet (5).
Refer to your site EBP or Research representative
to determine appropriate council
Yes
Yes
No
EVIDENCE-BASED PRACTICE (EBP) MODEL
NO- Cycle
complete
go back to
literature
Use the PDSA model to plan & conduct the pilot.
Resources: PDSA for Piloting Change Worksheet (6)
To implement project recommendations & conduct
education use the AHC Project Completion and
Education Planning Form (7)
Practice Change Communication
** Inform Shared Governance
Councils when needed
(ie, education and/or practice)
Is There
Sufficient
Evidence?
Adopt practice
change?
www.ccnonline.org CriticalCareNurse Vol 36, No. 4, AUGUST 2016 29
Observation Code Sheet is a flowsheet used to record
each medication administered during the observation
period and to tally each interruption observed during
the medication pass. Data collectors used the Medica-
tion Administration Accuracy Observation Code Sheet
to record each medication administered, including the
medication name, dose, route, and the time the medica-
tion was administered to the patient. Data collectors
were trained to record the reason for all interruptions
observed by using a free-text, narrative approach. The
project team planned to review the reasons for interrup-
tions after completion of the project and based on post-
hoc analysis, develop a scheme for categorizing the
sources of interruptions.
The Medication Administration Accuracy Record
Review Worksheet is a flowsheet used to identify
medication errors retrospectively by comparing medica-
tions administered during the observation period with
scheduled medication orders on the electronic medica-
tion administration record for the same time period.
Figure 2 Timeline for the Nurses Uninterrupted Passing Medications Safely (NUPASS) project’s pilot practice change.
Abbreviation: AACN, American Association of Critical-Care Nurses.
Attended AACN National
Teaching Institute, Chicago, Ilinois
(5/2009)
Measured % of interruptions and
medication errors after NUPASS
guideline implemented (12/2010)
Poster presentation at
AACN National
Teaching Institute, Boston,
Massachusetts (5/2012)
Measured % of interruptions and
medication errors before
NUPASS guideline
implemented (7/2009)
Pilot study (6/2009)
February
2010
November
2009
August
2011
November
2011
February
20
12
May
2012
February
2011
August
2009
May
2009
November
2010
May
2010
NUPASS guidelines
implemented (2/2010)
Initial internal presentation
of results (6/2011)
Remedial education for
intervention units (8/2010)
Analysis and interpretation
of results (5/2011)
Completed internal
presentation of results
(9/2011)
May
2011
August
2010
Table 4 Nurses Uninterrupted Passing Medications Safely (NUPASS) pilot practice change: operational definitions
Term
Interruption
Avoidable interruptions
Unavoidable interruptions
Medication error
Medication pass
Medication administration process
Definition
An event that halts the process of administering medication, causing the nurse to stop
the task of carrying out a step in the medication administration process and then return
to the medication administration process following disruption by another task or event.
Situations that could be managed by other staff members without risk of patient harm
while the nurse was administering medications. Examples include phone messages from
family members, responding to call lights, and nonemergent communication with staff in
other disciplines.
Situations that required immediate action by the nurse to maintain patient safety. Examples
include acute changes in patients’ status, responding to critical laboratory values, and
verifying and accessing information that may have a critical effect on patients’ outcomes
(eg, a question regarding the exact time a continuous intravenous infusion of heparin was
stopped before proceeding with a scheduled lumbar puncture).
A medication administered to the patient differently than ordered by the physician.
Administration of all medications to a single patient during a scheduled, peak administration time.
The process of administering medications, including medication preparation, administration,
and documentation.
30 CriticalCareNurse Vol 36, No. 4, AUGUST 2016 www.ccnonline.org
Following the observed medication passes, data col-
lectors used the Medication Administration Accuracy
Record Review Worksheet to reconcile the electronic
medication orders with the medications actually admin-
istered to the patients to identify medication errors.
The number and type of medication errors identified
were recorded on the data collection tool, including
wrong drug, dose, form, route, and technique and
omission of drug dose errors.
Communication Strategies
Once baseline data collection was complete on all 3
units, the project team trained the PCCU1 and PCCU2
nursing staff how to implement the NUPASS guidelines.
Staff members were trained to use communication scripts
to respond to nonemergent requests when nurses were
passing medications. The communication script simply
stated, “For the safety of our patients, the nurses are not
interrupted while passing medications. Is there some-
thing I can help you with?” Use of the phrase “for the
safety of our patients” was essential to avoid misconcep-
tions that the nurse was just “too busy” to speak to them.
The unit secretary managed most communication with
visitors and requests for clerical assistance from physi-
cians and other health care providers while the charge
nurse was responsible for addressing patient care
issues with phy-
sicians and
other care pro-
viders. The
nursing staff
was provided with operational definitions of emergen-
cies as part of the NUPASS guidelines; however, because
no guidelines address all situations, the members of the
nursing staff were coached to consider if a safety concern
existed before deciding whether or not to interrupt a
nurse during a medication pass.
The nurses and PCAs coordinated patient care
activities by alternating hourly patient care rounds to
ensure that the timing of nursing rounds corresponded
to the peak times for administering scheduled medications.
Purposeful, hourly rounding has been demonstrated to
decrease patients’ use of call lights and was a best prac-
tice established on the PCCUs before the pilot project
change.23 However, as part of the pilot practice change,
nurses wore a yellow safety sash during scheduled, peak
medication administration times as a visible sign that
they were passing medications and were not to be dis-
turbed. Before beginning the medication pass, nurses also
placed a colored magnet next to their name on the assign-
ment board to alert other care providers that they were in
the process of passing medications. Because the PCCU
assignment boards were in clear view from the centralized
nursing stations, this tactic provided another visible sign
to alert others of the medication pass. Once nurses were
done administering medications, they removed their yel-
low safety sash, picked up their docked phone, removed
the magnet from the assignment board, and checked with
the charge nurse for any logged messages or updates.
Educational Strategies
Unit staff, physicians, and other care providers hospital-
wide were educated on the pilot practice change, includ-
ing the purpose of the project and instructions for
communicating and coordinating care during scheduled,
peak medication administration times. Care providers
from numerous departments (pharmacy, rehabilitation,
nutrition, cardiodiagnostics, emergency, and transpor-
tation service) were educated in 6 months. Education
strategies included staff newsletters tailored to specific
departments, poster presentations, unit-based in-service
training programs, and presentations at scheduled staff
and physician meetings. Upon admission to PCCU1
and PCCU2, a patient-specific newsletter (Table 5) was
used to educate patients and their families about the
pilot project change.
Results
During the pilot practice change, 130 medication
passes were observed on the 3 PCCUs, including 64
medication passes before and 66 medication passes after
guideline implementation. During the 130 medication
passes, nurses were observed administering 631 medica-
tions: 316 medications before and 315 after guideline
implementation. The mean number of medications
administered per patient was 4.10, and the mean dura-
tion of medication passes was 11.69 minutes. Neither
the mean number of medication doses nor the duration
of medication passes differed significantly between units
before or after guideline implementation.
Interruptions
To answer the first question, the percentage of inter-
ruptions decreased significantly in 1 of the 3 PCCUs after
The project team staff nurses collected
all data and observed medication
passes on PCCUs other than their own.
www.ccnonline.org CriticalCareNurse Vol 36, No. 4, AUGUST 2016 31
implementation of the NUPASS guidelines. Interruptions
decreased from 23% to 4% (P < .001) in PCCU1 after imple-
mentation of the NUPASS guidelines. In comparison,
the percentage of interruptions did not change signifi-
cantly in PCCU2, and although the change was not sta-
tistically significant, the percentage increased in PCCU3
after guideline implementation (Table 6). Based on post-
hoc analysis, interruptions were categorized in 2 different
ways: (1) source of the interruption and (2) avoidable
versus unavoidable interruptions.
Four main sources of interruptions were identified:
(1) patient-related, (2) phone calls, (3) verbal (face-to-face
interaction), and (4) unavailability of resources (Figure 3).
Most of the decrease in interruptions after guideline
implementation was due to a 48% reduction in phone calls.
The second largest source of interruptions both before
and after implementation of the NUPASS guidelines
was the unavailability of resources. Of these, 85% were
because the nurse had to stop and get water or a cup
for the patient before administering medications.
In comparison, missing equipment and other supplies
accounted for only 15% of the interruptions in this cate-
gory. The majority of phone calls and verbal (face-to-face)
interruptions were related to patient care activities
including requests from patients, unit personnel, and
other care providers. Interruptions by physicians during
the pilot practice change accounted for only 7% of the
total interruptions. Patient-related sources of interruptions
Table 5 Patient medication safety newsletter
You may hear today:
“For the safety of our patients, we do not interrupt the nurses while they are administering medications. Is there something I can
assist you with?”
A team of nurses is conducting a project to improve patient safety. The purpose of the project is to increase patient safety by
limiting interruptions during medication administration.
Why is this project important? Numerous studies suggest that interruptions during medication administration contribute to
medication errors.
How are interruptions limited when the nurses are administering medications? Nurses will not take phone calls or respond
to inquiries from others including nursing staff, therapists, physicians, patients, and families when they are administering
medications EXCEPT for emergencies during these times:
8 to 10 AM
8 to 10 PM
5 to 7 AM
How will I know when the nurse is administering medications?
Nurses will wear a yellow safety sash to signify that they are administering medications and are not to be interrupted. Limiting inter-
ruptions allows the nurses to keep their attention focused on medication administration and the needs of the each patient who is
receiving medications.
What if I need to communicate with my nurse?
• The phone numbers of your nurse and patient care assistant (“PCA”) are posted on your communication board. You can call them
directly to avoid waiting for your call light to be answered.
• When your nurse is administering medications, his/her calls will be automatically forwarded to the front desk for further assistance.
• The nurse and the PCA take turns rounding at your bedside hourly to offer assistance so that your needs are met promptly.
• If you need help to the bathroom, with bathing, or need something to drink or eat, you can call your PCA.
Who can I talk to if I have more questions about the project? Your nurse will be able to answer most questions. Please also feel
free to direct any questions or comments to the Manager or Advanced Practice Nurse during their daily rounds. This project is a
team effort, and we need your help and support to make it a success!
Thank you from the project team!
Table 6 Interruptions before and after Nurses
Uninterrupted Passing Medications Safely (NUPASS) guide-
lines were implemented
Progressive
cardiac care unit
(PCCU)
PCCU1
(intervention unit)
PCCU2
(intervention unit)
PCCU3
(comparison unit)
Before
NUPASS
22/95 (23%)
25/118 (21%)
10/103 (10%)
After
NUPASS
5/113 (4%)
22/99 (22%)
15/103 (15%)
P
<.001
.46
.24
32 CriticalCareNurse Vol 36, No. 4, AUGUST 2016 www.ccnonline.org
did not differ before or after the implementation of the
NUPASS guidelines.
Avoidable interruptions decreased from 18 to 3 (83%)
in PCCU1 and from 19 to 9 (53%) in PCCU2 while avoid-
able interruptions in PCCU3 increased from 7 to 12
(71%) after implementation of the NUPASS guidelines
(Figure 4). Although PCCU2 did not show a statistically
significant decrease in the total percentage of interrup-
tions following implementation of the NUPASS guidelines,
the unit was successful in decreasing avoidable interrup-
tions by more than half. Unavoidable interruptions
decreased from 4 to 2 (50%) in PCCU1, increased from 6
to 14 (133%) in PCCU2 and increased from 1 to 2 (100%)
in PCCU3 after implementation of the NUPASS guidelines.
Medication Errors
To answer the second question, the percentage of
medication errors decreased in all 3 PCCUs after imple-
mentation of the NUPASS guidelines (Table 7). A statis-
tically significant decrease in the percentage of medication
errors was found in 1 of the 2 intervention units and in
the comparison unit. The percentage of medication
errors in PCCU1 decreased from 11% to 3% after the
guidelines were implemented (P = .02). Although the
percentage of medication errors in the second interven-
tion unit (PCCU2) decreased from 2% to 1%, the number
of observations conducted was not powered to demon-
strate a statistically significant change between such low
percentages of medication errors. An unanticipated find-
ing was a significant decrease in the percentage of medi-
cation errors (P = .01) in the comparison unit (PCCU3).
Discussion
Interruptions
Consistent with the findings of numerous pub-
lished studies, nurses observed during the pilot practice
change were frequently interrupted during medication
administration.6-8,11,12 In addition, results of the pilot
practice change support earlier reports that the majority
of interruptions during medication administration are
avoidable and may lead to adverse consequences for
patients.16,31 The greatest impact of implementing the
NUPASS guidelines was the significant decrease in avoid-
able interruptions, particularly those related to phone
Di i
Table 7 Medication errors before and after Nurses
Uninterrupted Passing Medications Safely (NUPASS)
guidelines were implemented
Progressive
cardiac care unit
(PCCU)
PCCU1
(intervention unit)
PCCU2
(intervention unit)
PCCU3
(comparison unit)
Before
NUPASS
10/95 (11%)
2/118 (2%)
9/103 (9%)
After
NUPASS
3/113 (3%)
1/99 (1%)
1/103 (1%)
P
.02
.57
.01
did diff b f f h i l i f h
Figure 3 Number of interruptions by source before and
after Nurses Uninterrupted Passing Medications Safely
(NUPASS) project.
N
o.
o
f i
nt
er
ru
pt
io
ns
Source
Patient
related
Before NUPASS After NUPASS
Phone
calls
Verbal UnknownResource
unavailable
25
20
15
10
5
0
Figure 4 Avoidable and unavoidable interruptions before
and after Nurses Uninterrupted Passing Medications
Safely (NUPASS) project.
N
o.
o
f i
nt
er
ru
pt
io
ns
Progressive cardiac care unit (PCCU)
PCCU1 PCCU2 PCCU3
Avoidable before NUPASS
Avoidable after NUPASS
Unavoidable before NUPASS
Unavoidable after NUPASS
18
16
14
12
20
10
8
6
4
2
0
www.ccnonline.org CriticalCareNurse Vol 36, No. 4, AUGUST 2016 33
calls. Successfully decreasing interruptions related to
phone calls was highly dependent on teamwork and
highlights the important role of support staff in priori-
tizing and managing phone calls during peak scheduled
medication administration times.
An important paradigm shift for PCCU nurses was
to assume accountability for interruptions, including
avoiding social chatter in the medication room and dele-
gating or deferring tasks when appropriate to main-
tain a concentrated focus on medication administration.
The pilot project team identified differences in unit cul-
ture, workflow demands throughout the 24-hour period,
visibility of leadership, and informal leadership support
on each shift as factors that may have influenced nurs-
ing staff buy-in and adherence to the NUPASS guidelines.
Adherence to the guidelines by physicians, other care
providers, and patients was greatly enhanced by educa-
tion and the use of key messages. The most important
message for gaining cooperation and support from phy-
sicians was that the practice change was to help “manage”
rather than limit communication among care providers.
The responses of patients and their families were
overwhelmingly positive when the pilot practice change
was introduced, and they often shared how impressed
they were that the staff took the patients’ safety so seri-
ously. However, the fact that the number of patient-
related interruptions remained the same before and
after implementation of the NUPASS guidelines sug-
gests the need to reinforce patient education about the
pilot project change throughout the hospital stay such as
signage in the patients’ rooms and verbal reminders.
Although no clinically significant difference was found
in unavoidable interruptions before and after implemen-
tation of the NUPASS guidelines in PCCU1 or PCCU3, a
large increase in unavoidable interruptions occurred in
PCCU2 after guideline implementation; that increase
was attributed to orientation and training of newly hired
nurses during this period.
Medication Errors
It is not clear why the percentage of medication
errors in PCCU2 was lower than in the other 2 units at
baseline. The only observable difference between units
was that PCCU2 has 2 centralized medication rooms
compared with only 1 such room on the other 2 PCCUs.
In addition, the finding that the percentage of medica-
tion errors decreased significantly after guideline
implementation in the comparison unit (PCCU3), inde-
pendent of the percentage of interruptions, highlights
that numerous factors besides interruptions affect
patient safety outcomes.
Sustainability of the Pilot Practice Change
The Institute of Medicine recommends that nurses
be observed periodically to measure actual medication
errors rather than relying completely on voluntary
reporting of medication errors.2 Observation methods
to measure medication errors are useful for overcoming
pitfalls of traditional event reporting, including underre-
porting of errors.32-35 However, direct observation to
measure interruptions and medication errors is time-
and resource-intensive because it requires trained data
collectors and coordination of data collecting activities.
A novel quality improvement approach used at Stanford
Health Care for ongoing measurement of interruptions
and medication errors shared by Elisa E. Nguyen (e-mail
communication, May 22, 2015) is to observe nurses admin-
istering medications as part of regularly scheduled hos-
pital prevalence
studies. Regard-
less of the method
used for collecting
interruption and
medication error
data, ongoing monitoring for quality improvement and
regular, timely feedback to nursing staff regarding mea-
sured outcomes is essential to promote a culture of safety
and sustain results in high-reliability organizations.
After the official project was completed, the
NUPASS project team was not able to continue the
quality improvement monitoring activities to evaluate
the sustainability of the outcomes associated with the
pilot practice change because of time constraints,
nursing staff turnover, and lack of funding. Lack of a
sustainability plan for this project resulted in a drift
back to former practice and is consistent with the find-
ings of Freeman and colleagues,17 who evaluated the
use of a similar set of strategies to limit interruptions in
a single progressive care unit. However, in July 2014, a
modified version of the pilot practice change was imple-
mented in all patient care units as a best practice with
the leadership support of the medical center’s chief nurse
executive. A major change in the guidelines is that the
yellow safety sash has been replaced by a hand-held
Decreasing interruptions was
highly dependent on teamwork
and highlights the important role
of support staff.
34 CriticalCareNurse Vol 36, No. 4, AUGUST 2016 www.ccnonline.org
bar-code scanner as a visible sign that the nurse is
administering medications and is not to be disturbed.
Limitations of the Pilot Practice Change
Although approximately one-third of the PCCU
nurses participated in the project, use of a convenience
sample of nurses limits the representativeness of the
sample. Second, observations were limited to 3 specialty
units at a single site, preventing generalization of the
findings to other patient populations and health care
settings. Third, because the nurses were aware that they
were being observed, they may have followed adminis-
tration safety practices more consistently, leading to
fewer medication errors (Hawthorne effect). Finally,
the comparison unit (PCCU3) was restructured after
the baseline data were collected for the pilot practice
change. The restructuring involved cohorting cardio-
vascular surgical patients at a lower nurse to patient
ratio; both of these factors limit the use of PCCU3 as
a comparison unit.
Last, for the purposes of this project, the definition
of medication errors was limited to administering medi-
cations as ordered by the physician. However, progres-
sive care nurses continuously make clinical judgments
about the appropriateness of carrying out medication
orders. These
judgments are
based on the
patient’s clini-
cal status,
relevant labo-
ratory data,
and contraindications related to risks of complications
associated with diagnostic and interventional proce-
dures. The critical thinking and decision-making pro-
cesses involved in making these judgments represent
important monitoring and surveillance activities nurses
use to keep patients safe regardless of the prescribed
medication order.
Conclusions
Results of the NUPASS pilot practice change demon-
strate that using evidence-based strategies to limit inter-
ruptions during medication administration in the
progressive cardiac care setting decreases avoidable
interruptions and promotes patient safety. Recognizing
medication administration as a high-risk activity is
critical to transforming the culture and engaging nursing
staff to promote the kind of teamwork necessary to limit
avoidable interruptions during medication administra-
tion. In this pilot practice change, we evaluated the
impact of limiting interruptions during medication
administration during scheduled, peak administration
times. The impact of limiting interruptions on medica-
tion errors during unscheduled administration of medi-
cations including as-needed medications and initiation
and titration of high-risk intravenous infusions (eg,
antiarrhythmic and inotropic agents) administered in
the progressive care setting warrants further study.
Although no “magic bullet” is available to prevent
medication administration errors, the outcomes of this
project support the use of evidence-based strategies to
limit interruptions during medication administration
as part of a comprehensive medication safety program.
Bedside nurses have little control over the physical lay-
out of the patient care unit, the nurse to patient ratio,
or access to technological advances to prevent medica-
tion errors; however, they can successfully affect the work
environment to promote patient safety with little or no
cost to the organization by adopting evidence-based
strategies to limit work interruptions during high-risk
activities such as medication administration. ���
Acknowledgments
The authors thank project team members Dawn Hart, RN, BSN, and Sue Glavin,
RN, MSN, FNP, ANCC-BC, for their dedication and commitment to the project,
Wendy Tuzik Micek, RN, PhD, NEA-BC, and Nancy Gaziano, BA, for their editorial
assistance, and Susan Massatt, RN, MA, CCRN, NEA-BC, and Lynn Hennessy, RN,
MS, MBA, NE, for their administrative support.
Financial Disclosures
None reported.
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d tmore
To learn more about patient safety in the critical care setting, read
“Safety Culture in Australian Intensive Care Units: Establishing a
Baseline for Quality Improvement” by Chaboyer et al in the American
Journal of Critical Care, March 2013;22:93-102. Available at www
.ajcconline.org.
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An important paradigm shift for PCCU
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