Drug Analysis Narrated Powerpoint Presentation

Drug Analysis Narrated Powerpoint Presentation

You will prepare a narrated powerpoint presentation about a drug or medication of your choice and upload it to Blackboard. You must cite at least three sources. Pick a drug or medication of interest to you (if you need help finding a drug, a list of sources and possible options is included, but you are not limited to those suggestions) and obtain the structure of the drug (links to a few sites that provide drug structure and function information are also listed below). Once you have chosen a drug, please post your choice on the discussion board on the Blackboard site so I don’t see duplicates. In your presentation, you will discuss the structural and chemical properties of the drug, the disease/condition it is intended to treat, and how the drug functions. You are limited to 10-15 minutes, so you need to spend time figuring out what is most important and how to present that concisely. A general rule is to assume you will spend one minute per slide, so shoot for 10-15 slides and adjust from there. I will upload instructions on how to add narration to your powerpoint slides, if you don’t know.

Your presentation should minimally include information on the following:

1) Chemistry of the drug

· where and when the drug was first discovered and/or synthesized

· the structure of the drug and identification of the functional group(s) present

· a discussion of the functional groups present and how they affect the drug’s chemical properties (such as polarity, solubility, hydrogen bonding, etc.) and its function

· any other chemical information you find interesting.

2) Biochemistry of the drug

· basic biochemistry of the disease/condition the drug is intended to treat

· how the drug functions to treat the disease/condition

· details of the direct target (often a protein) of the drug (and/or the enzymes and/or pathways involved)

· any other biochemical information you find interesting

Drug structure and function links:

http://www.3dchem.com/

Chemistry and structure of medicines: a visual and interactive website showcasing the beautiful world of chemistry

https://go.drugbank.com/

Also provides structures and mechanism of action of drugs, among lots of other useful info

https://go.drugbank.com/biotech_drugs

(same as above, different entry point)

http://www.biopsychiatry.com/structures/index.html

Possible drug choices (you are not limited by the lists below):

General: cold/allergy/asthma, painkillers (over the counter or prescription), prevention of cardiovascular and coronary events (statins etc), ADHD, Diabetes (Avandia…), heartburn/reflux (Prevacid…), vitamins, stimulants, illicit drugs, supplements…

Antibiotics (introductory list below):

Kanamycin, Penicillins (penicillin, amoxicillin, methicillin), Cepahlosporins, methicillin, Tetracycline, Chloramphenicol,

macrolide

antibiotics

, Beta-lactams, Azithromycin, Vancomycin

Anti-virals:

Influenza:

Neuramindase inhibitors,

Tamiflu (Oseltamivir)

,

Zanamivir

(Relenza),

Laninamivir

(Inavir),

Peramivir

HIV/AIDS:

http://www.aidsmeds.com/list.shtml

Too many to list; may include the following classes of drug:

Reverse Transcriptase Inhibitors, Protease Inhibitors, Entry Inhibitors, Integrase inhibitors, Multi-class combination drugs

Others: Interferons (hepatitis), Acyclovir (herpes),

Cancer drugs

http://www.cancer.gov/cancertopics/druginfo/alphalist

(kinase inhibitors, Avastin, Tarceva(erlotinib), Gleevec, tamoxifen, Herceptin, many others. Most are cancer specific, so you can also search for drugs against a specific type of cancer.

High blood pressure medication: Angiotensin-converting enzyme (ACE) inhibitors, Angiotensin II receptor blockers, Beta blockers, Calcium channel blockers, Renin inhibitors (ex: Zestril, Cozaar, Levatol, diltiazem, Tekturna)

Presentation Rubric

1	2	3	4
Introduction	Does not give information about what to expect or why this is an important issue.	Some information was given, but significance of the issue/topic wasn’t clear.	Gives too much or too little information making the topic unclear.	Presents a concise lead-in to the presentation.
Scientific quality (x2)	Arguments were made with little or no scientific data.	The scientific data presented lacked details and supporting evidence.	Scientific data was thorough, but presenter lacked a clear understanding of the topic.	Scientific data was thorough and presented with clarity and a depth of understanding.
Accuracy	There are more than 4 pieces of information that are inaccurate and/or false.	There are 3-4 pieces of information that are inaccurate and/or false.	There are 1-2 pieces of information that are inaccurate and/or false.	There are no factual errors.
Content	Presentation provides a discussion of some of the required components. They are not linked.	Presentation provides a discussion of some of the required components. They are somewhat linked	Presentation provides a discussion of all the required components. They are somewhat linked.	Presentation provides a thorough but concise discussion of all the required components. They are presented in a way that illustrates how they are linked.
Presentation	Showed little evidence of thoughtful research. Presentation does not effectively communicate research findings. Presentation is completely ineffective and confusing.	Showed evidence of thoughtful research, but presentation was not clear; too broad a topic/issue of debate for the time frame. Content is confusing and slides are unorganized. Graphics are absent or difficult to read/interpret.	Effectively communicated the results of research to the audience, but presentation lacked overall quality. Slides are somewhat disorganized or too busy; Graphics/fonts used are difficult to read/interpret.	Effectively communicated the results of research to the audience; Slides are well-organized; transitions are logical; information is clear and understandable; graphics contribute to the understanding of the content; displayed creativity and originality.
Preparedness	Simply reads each word off of slide; content did not appear to be thoughtfully developed.	Shows little knowledge of subject; presentation was clearly unrehearsed;	Shows some knowledge of subject; presentation was “choppy” at times; appeared uncertain about what was next	Shows general knowledge of subject; presentation generally flowed well; content is thoughtfully developed
Quality of Supporting Resources	There were fewer than 3 resources for each side of the topic and none of them were scholarly.	There were fewer than 3 resources for one side of the topic and some of them were scholarly.	There were 3 or more resources for each side, and some from a scholarly source.	There were 3 or more resources for each side and were from scholarly sources.
Spelling and Grammar	Grammatical and spelling errors distract from the presentation.	Presentation has more than 5-6 grammatical or spelling errors.	Presentation has 3-4 spelling or grammatical errors.	Presentation has 1-2 spelling or grammatical errors.