Managerial Epidemiology
Managerial Epidemiology: Week 2
Critical Reflection Paper: Chapters 4 &5
Objective: To censoriously reveal your understanding of the readings and your ability to apply them to your Health care Setting.
ASSIGNMENT GUIDELINES (10%):
Students will frowningly analyze the readings from Chapter 4 and 5 in your textbook. This assignment is premeditated to help you valuation, analysis, and apply the readings to your Health Care setting as well as become the groundwork for all of your outstanding assignments.
You need to read the article (in the additional weekly reading resources localize in the Syllabus and also in the Lectures link) assigned for week 1 and develop a 2 page paper reflecting your understanding and ability to apply the readings to your Health Care Setting. Each paper must be typewritten with 12-point font and double-spaced with standard margins. Follow APA format when referring to the selected articles and include a reference page.
EACH PAPER SHOULD INCLUDE THE FOLLOWING:
1. Introduction (25%) Provide a ephemeral summary of the denotation (not a description) of each Chapter and articles you read, in your own words.
2. Your Critique (50%)
What is your reaction to the content of the articles?
What did you absorb about Descriptive and analytic epidemiology?
What did you acquire about the quality and utility of epidemiologic data?
Did these Chapter and articles change your thoughts epidemiologic data sources and its weaknesses? If so, how? If not, what remained the same?
3. Conclusion (15%)
Transiently recapitulate your thoughts & assumption to your critique of the articles and Chapter you read. How did these articles and Chapters impact your thoughts on the difference between secular trends and cohort effects?
Evaluation will be based on how clearly you respond to the above, in particular:
a) The clarity with which you critique the articles;
b) The depth, scope, and organization of your paper; and,
c) Your conclusions, including a description of the impact of these articles and Chapters on any Health Care Setting.
ASSIGNMENT DUE DATE:
The assignment is to be electronically posted no later than noon on Saturday, January 18, 2020.
Chapter 4
Descriptive Epidemiology:
Person, Place, Time
Learning Objectives
• State primary objectives of descriptive
epidemiology
• Provide examples of descriptive studies
• List characteristics of person, place, and
time
• Characterize the differences between
descriptive and analytic epidemiology
Descriptive vs. Analytic
Epidemiology
• Descriptive studies–used to identify a
health problem that may exist.
Characterize the amount and distribution
of
disease
• Analytic studies–follow descriptive
studies, and are used to identify the
cause of the health problem
Objectives of Descriptive
Epidemiology
• To evaluate and compare trends in
health and disease
• To provide a basis for planning,
provision, and evaluation of health
services
• To identify problems for analytic studies
(creation of hypotheses)
Descriptive Studies and
Epidemiologic Hypotheses
• Hypotheses–theories tested by gathering
facts that lead to their acceptance or
rejection
• Three types:
– Positive declaration (research hypothesis)
– Negative declaration (null hypothesis)
– Implicit question (e.g., to study association
between infant mortality and region)
Mill’s Canons of Inductive
Reasoning
• The method of difference–all the
factors in two or more places are the
same except for a single factor.
• The method of agreement–a single
factor is common to a variety of
settings. Example: air pollution.
Mill’s Canons
(cont’d)
• The method of concomitant variation–
the frequency of disease varies
according to the potency of a factor.
• The method of residues–involves
subtracting potential causal factors to
determine which factor(s) has the
greatest impact.
Method of Analogy
(MacMahon and Pugh)
• The mode of transmission and
symptoms of a disease of unknown
etiology bear a pattern similar to that
of a known
disease.
• This information suggests similar
etiologies for both diseases.
Three Approaches to
Descriptive Epidemiology
• Case reports–simplest category
of descriptive epidemiology
• Case series
• Cross-sectional studies
Case Reports and Case Series
• Case reports–astute clinical observations
of unusual cases of disease
– Example: a single occurrence of methylene
chloride poisoning
• Case series–a summary of the
characteristics of a consecutive listing of
patients from one or more major clinical
– Example: five cases of hantavirus pulmonary
syndrome
Cross-sectional Studies
•
Survey
s of the population to estimate
the prevalence of a disease or
exposure
– Example: National Health Interview
Survey
Characteristics of Persons
Covered in Chapter 4
•
Age
• Sex
•
Marital Status
• Race and ethnicity
• Nativity and
migration
•
Religion
• Socioeconomic
status
Age
• One of the most important factors to
consider when describing the
occurrence of any disease or illness
Trends by Age Sub
group
• Childhood to early adolescence
– Leading cause of death, ages 1-14
years—unintentional injuries
– Infants—mortality from developmental
problems, e.g., congenital birth defects
– Childhood—occurrence of infectious
diseases such as meningococcal
disease
Trends by Age Subgroup
(cont’d)
• Teenage years
– Leading causes of death—unintentional
injuries, homicide, and suicide
– Other issues—unplanned pregnancy,
tobacco use, substance abuse
Trends by Age Subgroup
(cont’d)
• Adults—leading causes of death
– Unintentional injuries
–
Cancer
– Heart disease
• Older adults—deaths from chronic diseases
(e.g., cancer and heart disease) dominate.
• Elderly—deaths from chronic diseases and
limitations in activities of daily living
Age Trends in Cancer Incidence
• Age-specific
rates
of cancer incidence
increase with age with apparent
declines late in life.
Reasons for Age Associations
• Validity of diagnoses across the life
span
• Multimodality of trends
• Latency effects
• Action of the “human biologic clock”
• Life cycle and behavioral phenomena
Validity of Diagnoses
• Classification errors
– Age-specific incidence rates among
older groups
• Exact cause of death can be inaccurate
due multiple sources of morbidity that affect
elderly.
Age-Specific Distributions of
Disease Incidence
• Age-specific distributions of disease incidence
can be linear or multimodal.
– Linear trend—incidence of cancer
– Multimodal (having several peaks in incidence)
• Tuberculosis—peaks at ages 0 to 4 and ages 20-29
• Meningococcal disease—peaks among infants younger
than age 1 year and teenagers about 18 years old
Latency Effects
• Age effects on mortality may reflect
the long latency period between
environmental exposures and
subsequent development of disease.
Biologic Clock Phenomenon
• Waning of the immune system may
result in increased susceptibility to
disease, or aging may trigger
appearance of conditions believed to
have genetic basis.
– Example: Alzheimer’s disease
Sex Differences: Males
• All-cause age-specific mortality
rates is higher for men than for
women.
– May be due to social factors
– May have biological basis
• Men often develop severe forms of
chronic disease.
• Generally, death rates for both
sexes are declining.
Sex Differences: Female Paradox
• Reports from the 1970s indicated female
age-standardized morbidity rates for many
acute and chronic conditions were higher
than rates for males, even though
mortality was higher among males.
• Higher female rates for:
– Pain
– Asthma
– Some lung difficulties
Cancer
• Cancer of the lung and bronchus is
leading cause of cancer death for
both men and women in the
U.S.
• Increases among women are related
to changes in lifestyle and risk
behavior, e.g., smoking.
CHD among Women
• Coronary heart disease (CHD) is the
leading cause of mortality among
women (and also men).
• Women may not be alert for
symptoms of CHD and fail to seek
needed treatment.
Minority Women in Economically
Disadvantaged U.S. Areas
• In Los Angeles County, some have
higher rates of diabetes and
hypertension than men.
• A large percentage are physically
inactive.
• High rates of obesity among Latinas
and African Americans.
Marital Status
• Categories
–Single or non-married (e.g., never
married, divorced, widowed)
–Married
–Living with a partner
Marital Status (cont’d)
• In general, married people tend to
have lower rates of morbidity and
mortality.
– Examples: chronic and infectious
diseases, suicides, and accidents.
• Never married adults (especially
men) less likely to be overweight
Marital Status (cont’d)
• Marriage may operate as a protective
or selective factor.
– Protective hypothesis: marriage
provides an environment conducive to
health.
– Selective hypothesis: people who marry
are healthier than people who never
marry.
Marital Status (cont’d)
• Widowed
persons
–Suicide rates
• Elevated among young white males
who were widowed
–Depression
• Elevated rates among widowed
persons
General Comments About Race
• U.S. is becoming increasingly more
diverse.
• Race is an ambiguous concept that
overlaps with other dimensions.
• Some scientists propose that race is
primarily a social and cultural
construct.
Measurement of Race
• Census 2000 changed the race category
by allowing respondents to choose one or
more race categories.
• Census 2000 used five categories of race.
• Census 2010 continued with this
classification scheme (Refer to Exhibit 4-1
in text).
Race/Ethnicity Categories
Discussed in Chapter 4
• African American
• American Indian
• Asian
• Hispanic/Latino
African Americans
• In a classic study of differential mortality in U.S.,
they had the highest rate of mortality of all
groups studied.
• Higher blood pressure levels
– Possible influence of stress or diet.
– Higher rates of hypertensive heart disease.
• In 2007, age-adjusted death rate for African
Americans was 1.3 times rate for whites.
• Differences in life expectancy
American Indians/Alaska
Natives
• High rates of chronic diseases, adverse
birth outcomes, and some infectious
diseases
• Pima Indians (1975-1984 data):
– High mortality, e.g., male death rate (ages
25 to 34) was 6.6 times that for all races in
U.S.
– Infectious diseases were the 10th leading
cause of death.
Asians
• Japanese Americans have lower mortality
rates than whites.
– Lower rates of CHD and cancer.
– Low CHD rates attributed to low-fat diet and
institutionalized stress-reducing strategies.
• Some Asian groups, e.g., Cambodian
Americans, have high smoking
rates.
• TB rates are highest among Asian/Pacific
Islander group.
Acculturation
• Defined as modifications that
individuals or groups undergo when
they come in contact with another
country
– Provides evidence of the influence of
environmental and behavioral factors
on chronic disease
• Example: Japanese migrants experience
a shift in rates of chronic disease toward
those of the host country.
Hispanics/Latinos
• Hispanic Health and Nutrition
Examination Survey (HHANES).
– Examined health and nutrition status of
major Hispanic/Latino populations in the
U.S.
• San Antonio Heart Study
– Found high rates of obesity and diabetes
among Mexican Americans
• Hispanic mortality paradox (text box)
Nativity and Migration
• Nativity–Place of origin of the
individual
• Categories are foreign born and
native born.
• Nativity and migration are related.
Impact of Migration
• Importation of “Third World” disease by
immigrants from developing countries
– Leprosy during 1980s
• Programmatic needs resulting from
migration:
– Specialized screening programs (tuberculosis
and nutrition)
– Familiarization with formerly uncommon (in
U.S.) tropical diseases
Healthy Migrant Effect
• Observation that healthier, younger
persons usually form the majority of
migrants
– Often difficult to separate environmental
influences in the host country from
selective factors operative among those
who choose to migrate
Religion
• Certain religions prescribe lifestyles
that may influence rates of morbidity
and mortality.
– Example: Seventh Day Adventists
• Follow vegetarian diet and abstain from
alcohol and tobacco use
• Have lower rates of CHD, reduced cancer
risk, and lower blood pressure
• Similar findings for Mormons
Socioeconomic Status
• Low social class is related to excess
mortality, morbidity, and disability
rates.
– Factors include:
• Poor housing
• Crowded conditions
• Racial disadvantage
• Low income
• Poor education
• Unemployment
Measurement of Social
Class
• Variables include:
– Prestige of occupation or social position
– Educational attainment
– Income
– Combined indices of two or more of the
above variables
Hollingshead and Redlich
• Studied association of socioeconomic
status and mental illness
• Classified New Haven, Connecticut,
into five social classes based on
occupational prestige, education, and
address
Hollingshead and Redlich
Findings
• Strong inverse association between
social class and likelihood of being a
mental patient under treatment.
• As social class increased, severity
of mental illness decreased.
• Type of treatment varied by social
class.
Mental Health and Social
Class
• In the U.S., the highest incidence of
severe mental illness occurs among
the lowest social classes.
Mental Health and Social
Class: Two Hypotheses
• Social causation explanation (breeder
hypothesis)—conditions associated with
lower social class produce mental
illness.
• Downward drift hypothesis—Persons
with severe mental disorders move to
impoverished areas.
Other Correlates of Low Social
Class
• Higher rate of infectious disease
• Higher infant mortality rate and overall
mortality rates
• Lower life expectancy
• Larger proportion of cancers with poor
prognosis
– May be due to delay in seeking health care
• Low self-perceived health status
Characteristics of Place
• Types of place comparisons:
– International
– Geographic (within-country) variations
– Urban/rural differences
– Localized occurrence of disease
International Comparisons of
Disease Frequency
• World Health Organization (WHO) tracks
international variations in rates of disease.
• Infectious and chronic diseases show great
variation across countries.
• Variations are attributable to climate, cultural
factors, dietary habits, and health care access.
• The U.S. fell in the bottom half of OECD
countries for both male and female life
expectancy; Japan was highest.
Within-Country Variations in
Rates of
Disease
• Due to variations in climate, geology, latitude,
pollution, and ethnic and racial concentrations
• In U.S., comparisons can be made by region,
state, and/or county.
– Examples include: higher rates of leukemia in
Midwest; state by state variations in
infectious, vector-borne, parasitic diseases
Urban/Rural Differences in
Disease Rates
• Urban
– Diseases and mortality associated with crowding,
pollution, and poverty
– Example: lead poisoning in inner cities
– Homicide in central cities
• Rural
– Mortality (among all age groups) increases with
decreasing urbanization.
– Health risk behaviors higher in rural South
Standard Metropolitan
Statistical Areas (SMSAs)
• Established by the U.S. Bureau of
the Census to make regional and
urban/rural comparisons in disease
rates
Metropolitan Statistical Areas
(MSAs)
• Provide a distinction between
metropolitan and nonmetropolitan
areas by type of residence,
industrial concentration, and
population concentration
Definition of MSA
• Used to distinguish between metropolitan
and nonmetropolitan areas
• Metropolitan area—large population
nucleus together with adjacent
communities
• Six urban-classification levels used by the
National Center for Health Statistics (refer
to text.)
Census Tracts
• Small geographic subdivisions of cities,
counties, and adjacent areas
• Each tract contains about 4,000 residents.
• Are designed to provide a degree of
uniformity of population economic status
and living conditions in each tract
Localized Place Comparisons
• Disease patterns are due to unique
environmental or social conditions
found in particular area of interest.
Examples include:
– Fluorosis: associated with naturally
occurring fluoride deposits in water.
– Goiter: iodine deficiency formerly found
in land-locked areas of U.S.
Geographic Information
Systems (GIS)
• A method to provide a spatial
perspective on the geographic
distribution of health conditions
• A GIS produces a choroplath map
that shows variations in disease rates
by different degrees of shading.
Reasons for Place Variation in
Disease
• Gene/environment interaction
– Examples: sickle-cell gene; Tay-Sachs
disease.
• Influence of climate
– Examples: yaws, Hansen’s disease
• Environmental factors
– Example: chemical agents linked to cancer
Characteristics of Time
• Cyclic fluctuations
• Point epidemics
• Secular time trends
•
Clustering
– Temporal
– Spatial
Cyclic Fluctuations
• Periodic changes in the frequency of diseases
and health conditions over time
• Examples:
• Birth rates
• Higher heart disease mortality in winter
• Influenza
• Unintentional injuries
• Meningococcal disease
• Rotavirus infections
Cyclic Fluctuations (cont’d)
• Related to changes in lifestyle of the
host, seasonal climatic changes, and
virulence of the infectious agent
Common Source Epidemic
• Outbreak due to exposure of a group
of persons to a noxious influence that
is common to the individuals in the
group
– Types: point epidemic; continuous
common source epidemic
– Refer to Figure 4-22 for an example an
influenza outbreak in a residential
facility.
Point Epidemics
• The response of a group of people
circumscribed in place and time to a
common source of infection,
contamination, or other etiologic factor to
which they were exposed almost
simultaneously.
• Examples: foodborne illness; responses to
toxic substances; infectious diseases.
Influenza-Related Illness at a
Residential Facility
Secular Time Trends
• Refer to gradual changes in the
frequency of a disease over long time
periods.
• Example is the decline of heart
disease mortality in the U.S.
– May reflect impact of public health
programs, dietary improvements, better
treatment, or unknown factors.
Clustering
• Case clustering–refers to an unusual
aggregation of health events grouped
together in space and time
– Temporal clustering: e.g., post-
vaccination reactions, postpartum
depression
– Spatial clustering: concentration of
disease in a specific geographic area,
e.g., Hodgkin’s disease
Chapter 5
Sources of Data for Use in
Epidemiology
Learning Objectives
• Discuss criteria for assessing the quality
and utility of epidemiologic data
• Indicate privacy and confidentiality issues
that pertain to epidemiologic data
• Discuss the uses, strengths, and
weaknesses of various epidemiologic data
sources
Criteria for the Quality and
Utility of Epidemiologic Data
• Nature of the data
• Availability of the data
• Completeness of population
coverage
– Representativeness
– Generalizability (external validity)
– Thoroughness
• Strengths versus limitations
Nature of the Data
• Refers to the source of data, e.g.,
vital statistics, case registries,
physicians’ records, surveys of the
general population, or hospital and
clinic cases.
• Will affect the types of statistical
analyses and inferences that are
possible.
Availability of the Data
• Refers to investigator’s access to
data.
• For example, medical records and
other data with personal identifiers
may not be used without patients’
consent.
Completeness of Population
Coverage
• Representativeness—the degree to which
a sample resembles a parent population.
• Generalizability (external validity)— ability
to apply findings to a population that did
not participate in the study.
• Thoroughness—the care taken to identify
all cases of a given disease.
Strengths versus Limitations
• The utility of the data for various
types of epidemiologic research.
• Factors inherent in the data may limit
their usefulness.
– Incomplete diagnostic information.
– Case duplication.
Online Sources of Epidemiologic
Data
• Online bibliographic databases include
MEDLINE, TOXLINE, and commercial
databases.
• National Library of Medicine’s PubMed®
– MEDLINE is the main part of PubMed®
– Premier source of health-related literature
• TOXLINE—keyed to toxicology and includes
information on drugs and chemicals
Selected Internet Addresses
• American Public Health Association—
http://www.apha.org
• Centers for Disease Control and
Prevention—http://www.cdc.gov
• PubMed®—
http://www.ncbi.nlm.nih.gov/sites/entr
ez
Confidentiality
• Privacy Act of 1974
– Prohibits the release of confidential data
without the consent of the individual
• Freedom of Information Act
– Mandates the release of government
information to the public, except for personal
and medical files
• The Public Health Service Act
– Protects confidentiality of information
collected by some federal agencies, e.g.,
NCHS
The HIPAA Privacy Rule
• Refers to the Health Insurance Portability and
Accountability Act of 1996
• Sections of HIPAA “…require the Secretary of
HHS to publicize standards for the electronic
exchange, privacy and security of health
information…”
• Categories of protected health information
pertain to individually identifiable data re:
– The individual’s physical and mental health
– Provision of health care to the individual
– Payment for provision of health care
Data Sharing
• Refers to the voluntary release of
information by one investigator or
institution to another for the purpose of
scientific research.
• Can enhance data quality and increase
knowledge from research.
• Key issue is the primary investigator’s
potential loss of control over information.
Record Linkage
• Joining data from two or more
sources, e.g., employment records
and mortality data.
• Applications include genetic research,
planning of health services, and
chronic disease tracking.
Statistics Derived from the
Vital Registration System
• Mortality statistics
• Birth statistics: certificates of birth
and fetal death.
Mortality Statistics
• Mortality data are nearly complete, as
most deaths in the U.S. and other
developed countries are unlikely to be
unreported.
• Death certificates include demographic
information about the deceased and cause
of death (immediate cause and
contributing factors).
Limitations of Mortality Data
• Certification of cause of death.
– For example, in an elderly person with
chronic illness, exact cause of death may be
unclear.
• Lack of standardization of diagnostic criteria.
• Stigma associated with certain diseases, e.g.,
AIDS, may lead to inaccurate reporting.
Limitations of Mortality Data
(cont’d)
• Errors in coding by nosologist
• Changes in coding
– Revisions in the (ICD) International
Classification of Disease.
– Sudden increases or decreases in a
particular cause of death may be due to
changes in coding.
Birth Statistics: Certificates of Birth
and of Fetal Death
• Birth certificate includes information that
may affect the neonate, such as
congenital malformations, birth weight,
and length of gestation.
• Sources of unreliability:
– Mothers’ recall of events during pregnancy
may be inaccurate.
– Conditions that affect neonate may not be
present at birth.
Birth Statistics (cont’d)
• Varying state requirements for fetal death
certificates.
• Both types of certificates have been used
in studies of environmental influences
upon congenital malformations.
• Both provide nearly complete data.
Reportable
Disease Statistics
• Federal and state statutes require health care
providers to report those cases of diseases
classified as reportable and notifiable.
– Include infectious and communicable
diseases that endanger a population, e.g.,
STDs, measles, foodborne illness.
Limitations of Reportable
Disease Statistics
• Possible incompleteness of population
coverage.
– For example, asymptomatic persons
would not seek treatment.
• Failure of physician to fill out required
forms.
• Unwillingness to report cases that carry a
social stigma.
Screening
Survey
s
• Conducted on an ad hoc basis to identify
individuals who may have infectious or
chronic diseases. Examples: breast
cancer screenings, health fairs.
• Clientele are highly selected.
– Individuals who participate are concerned
about the particular health issue.
Multiphasic Screening
• Administration of 2 or more screening
tests during a single screening program
• Ongoing screening programs often are
carried out at worksites.
• Potential biases from worker attrition
• Data can be useful for research on
occupational health problems.
• Data may not contain etiologic information.
Disease Registries
• Registry–a centralized database for collection
of data about a disease
• Coding algorithms are used to maintain patient
confidentiality.
• Applications of registries:
– Patient tracking
– Identification of trends in rates of disease
– Case-control studies
• Example: SEER program
Surveillance, Epidemiology, and
End Results (SEER) Program
• Conducted by the National Cancer
Institute (NCI)
• Collects cancer data from different cancer
registries across the U.S.
• Provides information about trends in
cancer incidence, mortality, and survival
Morbidity Surveys of the
General Population
• Morbidity surveys collect data on the
health status of a population group.
• Obtain more comprehensive information
than would be available from routinely
collected data
• Example:
National Health Interview
Survey
National Health Survey
• Authorized under the National Health
Survey Act of 1956 to obtain information
about the health of the U.S. population.
• Refers generically to a group of surveys
and not a single survey.
• In response to the Act, the National Center
for Health Statistics (NCHS) conducts
three separate and distinct programs.
NCHS Survey Programs
• National Health Interview Survey
(NHIS)
• Health Examination Survey
(HES)
• Various surveys of health resources
– National Hospital Discharge Survey
– National Ambulatory Medical Care
Survey
National Health Interview
Survey (NHIS)
• General household health survey of the
U.S. civilian noninstitutionalized
population
• Studies a comprehensive range of
conditions such as diseases, injuries,
disabilities, and impairments
Health Examination Survey
(HES)
• Provides direct information about morbidity
through examinations, measurements, and
clinical tests
– Identifies conditions previously unreported or
undiagnosed
– Provides information not previously available
for a defined population
• Now known as the Health and Nutrition
Examination Survey (HANES)
Behavioral Risk Factor
Surveillance System (BRFSS)
• Collects data on behaviorally related
phenomena
– Behavioral risks for chronic diseases
– Preventive activities
– Healthcare utilization
• The largest telephone survey in the world
California Health Interview
Survey (CHIS)
• Provides information on the health and
demographic characteristics of California
residents
• Uses telephone survey methods
• Topics include
– Physical and mental health
– Health behaviors
– Health insurance coverage and utilization
• Conducted on a continuing basis
Insurance Data
• Sources include:
– Social Security–provides data on disability
benefits and Medicare.
– Health insurance–provides data on those
who receive care through a prepaid medical
program.
– Life insurance–provides information on
causes of mortality; also provides results of
physical examinations.
Limitations of Insurance Data
• Data may not be representative of
entire population, as the uninsured
are excluded.
Clinical Data Sources
• Hospital data
• Diseases treated in special clinics
and hospitals
• Data from physicians’ practices
Hospital Data
• Consists of both inpatient and outpatient
data
• Deficiencies of data:
– Not representative of any specific
population
– Different information collected on each
patient
– Settings may differ according to social
class of patients; e.g., specialized
clinics, emergency rooms
Diseases Treated in Special
Clinics and Hospitals
• Data cannot be generalized because
patients are a highly selected group.
• Case-control studies can be done with
unusual and rare diseases.
– However, it is not possible to
determine incidence and prevalence
rates without knowing the size of the
denominator.
Data from Physicians’
Practices
• Limited application due to:
– Confidentiality of patient data
– Highly selected group of patients
– Lack of standardization of information
collected
• Useful for the purposes of:
– Verification of self-reports
– Source of exposure data
Absenteeism Data
• Records of absenteeism from work or
school
• Possible deficiencies:
– Data omit people who neither work nor
attend school.
– Not all people who are ill take time off.
– Those absent are not necessarily ill.
• Useful for the study of rapidly spreading
conditions
School Health Programs
• Provide information about
immunizations, physical exams, and self-
reports of illness
• Have been used in studies of
intelligence, mental retardation, and
disease etiology
• Paffenbarger, et al. used information
from health records of college students
to track causes of chronic diseases.
Morbidity Data from the
Armed Forces
• Reports from physicals, hospitalizations, and
selective service examinations
• Data have been used for:
– Studies of disease etiology.
• Study of twins serving in Korean War or WWII to
determine influence of “nature and nurture” on
cause of disease.
– Studies investigating genetic factors in
obesity
Other Data Sources Relevant
to Epidemiologic Studies
• U.S. Bureau of the Census publications:
– Statistical Abstract of the United States
– County and City Data Book
– Decennial Censuses of Population and
Housing
– Historical Statistics of the United States,
Colonial Time to 1970
U.S. Bureau of the Census
• Provides information on the general, social, and
economic characteristics of the U.S. population
• U.S. Census is administered every 10 years.
– Attempts to account for every person and his
or her residence
– Characterizes population according to sex,
age, family relationships, and other
demographic variables